中国草食动物科学2024，Vol.44Issue(4)：62-67,6.DOI:10.3969/j.issn.2095-3887.2024.00.066
蛋白磷酸化修饰调控卵母细胞成熟的研究进展
Research Progress on the Regulation of Protein Phosphorylation on Oocyte Maturation
摘要
Abstract
The orderly progression of meiosis in mammalian oocytes is a prerequisite for successful fertilization and subsequent embryonic development,as well as the foundation for sexual reproduction.Studies have shown that many protein phosphorylation modification events are important for regulating meiotic arrest or recovery,chromosome sepa-ration,and proper spindle assembly.The article provided an overview of the role of phosphorylation modification in oocyte maturation,with a focus on the important roles played by CDK1,ERK,AURKs,PKB,Haspin,and PP1/PP2A in oocyte maturation,in order to provide reference for improving mammalian reproductive capacity and guiding female animal infertility.关键词
卵母细胞/磷酸化/减数分裂/蛋白质Key words
oocyte/phosphorylation/meiosis/protein分类
农业科技引用本文复制引用
郭韶珂,郭宪..蛋白磷酸化修饰调控卵母细胞成熟的研究进展[J].中国草食动物科学,2024,44(4):62-67,6.基金项目
国家自然科学基金项目(32272852) （32272852）
甘肃省科技计划科技特派团专项(23CXNH0016) （23CXNH0016）
财政部和农业农村部-现代农业(肉牛牦牛)产业技术体系建设专项(CARS-37) （肉牛牦牛）
中国农业科学院科技创新工程牦牛资源与育种(25-LZIHPS-01) （25-LZIHPS-01）
