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《代谢相关(非酒精性)脂肪性肝病防治指南(2024年版)》解读OACSTPCD

Interpretation and practical application of guidelines for the prevention and treatment of metabolic dysfunction-associated(non-alcoholic)fatty liver disease(Version 2024)

中文摘要英文摘要

随着肥胖和代谢综合征的流行,非酒精性脂肪性肝病(NAFLD)已取代慢性乙型肝炎成为中国第一大慢性肝病.随着对该疾病流行病学和自然史的深入研究、更名、诊断技术的飞速进步以及治疗手段的不断更新,NAFLD的诊疗领域经历了显著发展.最近,中华医学会肝病学分会组织相关专家对《非酒精性脂肪性肝病防治指南(2018更新版)》进行了全面修订,发布了《代谢相关(非酒精性)脂肪性肝病防治指南(2024年版)》.2024年版指南对代谢相关脂肪性肝病的疾病更名与分类、筛查和监测、诊断和评估、治疗和随访等重要临床问题提出了指导性建议.该文旨在通过对该诊疗指南的重要更新点进行解读,以帮助临床工作者更全面深刻地理解指南,并将其应用于指导临床实践.

With the prevalence of obesity and metabolic syndrome,non-alcoholic fatty liver disease(NAFLD)has replaced chronic hepatitis B as the leading chronic liver disease in China.In recent years,continuous exploration of the epidemiology and natural history of this disease,proposals for renaming,rapid advancements in diagnostic techniques,and continuous updates in treatment methods have propelled significant progress in the related diagnostic and therapeutic fields.Recently,experts in the Chinese Society of Hepatology revised the"Guidelines for the Prevention and Treatment of Non-Al-coholic Fatty Liver Disease(2018 Updated Version)"and published the"Guidelines for the Prevention and Treatment of Metabolic Dysfunction-associated(Non-alcoholic)Fatty Liver Disease(Version 2024)".The updated guideline provides guiding recommendations on important clinical issues such as renaming and sorting,screening and monitoring,diagnosis and assessment,treatment,and follow-up for this disease.This article aims to interpret the key updates in this guideline to help clinical practitioners gain a more comprehensive understanding and apply them to guide clinical practice.

曾静;范建高

上海交通大学医学院附属新华医院消化内科,上海市 200092

临床医学

代谢相关脂肪性肝病非酒精性脂肪性肝病指南

metabolic dysfunction-associated fatty liver diseasenon-alcoholic fatty liver diseaseguideline

《中国动脉硬化杂志》 2024 (007)

553-557 / 5

国家自然科学基金项目(82170593、82100605);国家重点研发计划项目(2021YFC2700802);上海交通大学交大之星计划项目(YG2021QN54)

10.20039/j.cnki.1007-3949.2024.07.001

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