中国防痨杂志2024，Vol.46Issue(8)：863-868,6.DOI:10.19982/j.issn.1000-6621.20240114
非结核分枝杆菌病诊治六十年
Diagnosis and treatment of nontuberculous mycobacteria diseases in the past 60 years
段鸿飞1
作者信息
- 1. 首都医科大学附属北京胸科医院/北京市结核病胸部肿瘤研究所结核科,北京 101149
- 折叠
摘要
Abstract
Nontuberculous mycobacteria(NTM)diseases have been recognized for over six decades,with progressively advancing levels of diagnosis and treatment.During the 1990s,a pivotal randomized controlled multicenter study demonstrated the efficacy of macrolide-based regimens against Mycobacterium avium complex infections.Concurrently,the advent of molecular biology techniques for bacterial identification supplanted traditional biochemical methods,greatly enhancing the capacity of medical institutions to diagnose and treat NTM infections.Recent years have witnessed critical developments,including the rapid identification of Mycobacterium species in clinical specimens,the recognition of reinfection as a primary cause of treatment failures in NTM disease,and the proven effectiveness of amikacin liposomes in treating Mycobacterium avium complex pulmonary disease.Drawing on experiences from tuberculosis management,future strategies for NTM should focus on developing rapid diagnostic tests for core drug sensitivities to facilitate the formulation of concise and effective treatment regimens.关键词
非典型性细菌/分枝杆菌感染/诊断/治疗应用Key words
Atypical mycobacteria/Mycobacterium infections/Diagnosis/Therapeutic uses分类
医药卫生引用本文复制引用
段鸿飞..非结核分枝杆菌病诊治六十年[J].中国防痨杂志,2024,46(8):863-868,6.
