中国感染控制杂志2024，Vol.23Issue(7)：798-805,8.DOI:10.12138/j.issn.1671-9638.20245324
环境卫生与医院感染的时间序列研究:基于广义相加模型(GAM)
Environmental hygiene and healthcare-associated infection:a time-series study based on generalized additive model
摘要
Abstract
Objective To quantitatively analyze the impact of environmental hygiene on the occurrence of health-care-associated infections(HAI).Methods Monitoring data of HAI and environmental hygiene from a tertiary first-class hospital from January 2018 to December 2022 were collected,and the impact of environmental bacterial colony forming unit(CFU)on the occurrence of HAI was analyzed by a time-series generalized additive model.Results The single-contamination model showed a significant positive correlation between HAI and staff's hand bacterial CFU(β1=0.009,P=0.012).For an increase of 1 interquartile range(IQR)in the monthly mean CFU per dish(MCFU/Dish)of staffs'hand,the incidence of HAI increased by 13.28％(95％CI:2.82％-24.81％).Subgroup and lag effect analysis showed that when the monthly MCFU/Dish(after hand disinfection)of staffs'hand in-creased by one IQR,the excess risk(ER)of HAI for the month(lag0)was 16.26％(95％CI:15.45％-17.09％).In the multi-contamination model,the correlation between surface contamination and HAI was also statistically sig-nificant.Conclusion There is a significant correlation between hospital environmental hygiene and the occurrence of HAI.关键词
医院感染/时间序列分析/广义相加模型/环境卫生/手卫生Key words
healthcare-associated infection/time-series analysis/generalized additive model/environmental hy-giene/hand hygiene分类
医药卫生引用本文复制引用
林凯,单欢,陈坤,王建炳,范芳华,梁辉,陈芳,金凯玲,储文杰,陈伟国..环境卫生与医院感染的时间序列研究:基于广义相加模型(GAM)[J].中国感染控制杂志,2024,23(7):798-805,8.基金项目
浙江省医药卫生科技计划项目(2021KY625) （2021KY625）
