中国康复理论与实践2024，Vol.30Issue(7)：831-838,8.DOI:10.3969/j.issn.1006-9771.2024.07.012
智能镜像手套任务导向性训练联合低频重复经颅磁刺激对脑卒中患者手功能效果的随机对照试验
Effect of intelligent mirror glove task-oriented training combined with low-frequency repetitive transcranial mag-netic stimulation on hand function in patients with stroke:a randomized controlled trial
摘要
Abstract
Objective To explore the effect of task-oriented training of intelligent mirror gloves combined with low-frequency repeti-tive transcranial magnetic stimulation(rTMS)on hand function recovery in stroke patients. Methods From October 1st,2022 to June 30th,2023,136 stroke patients in Northern Jiangsu People's Hospital were ran-domly divided into control group,mirror group,rTMS group and combination group,with 34 patients in each group.All the groups received routine rehabilitation treatment.In addition,the mirror group received task-orient-ed training of intelligent mirror gloves,rTMS group received low-frequency rTMS,and the combination group received task-oriented training combined with low-frequency rTMS,for four weeks.The Fugl-Meyer Assess-ment-Upper Extremities(FMA-UE)score,Wolf Motor Function Test(WMFT)score,and surface electromyo-graphic root mean square(RMS)of forearm extensor and flexor muscle groups on the affected/healthy side be-fore and after treatment were compared.And the differences of transcranial magnetic stimulation-motor-evoked potentials(MEP)between rTMS group and combination group before and after treatment were also compared. Results Four cases in the control group,seven in the mirror group,five in rTMS group and six in the combination group dropped off.The intra-group effect(F>996.656,P<0.001),inter-group effect(F>20.333,P<0.001)and inter-action effect(F>72.796,P<0.001)were significant in the scores of FMA-UE and WMFT,and the RMS ratio of forearm extensor and flexor muscle groups among four groups,in which the combination group was the best.After treatment,the amplitude of MEP increased in rTMS group and combination group(|t|>3.842,P<0.05),and was higher in the combination group than in rTMS group(t=-3.060,P<0.01). Conclusion The task-oriented training of intelligent mirror gloves combined with low-frequency rTMS could effectively promote the recovery of hand function in stroke patients.关键词
脑卒中/智能镜像手套/任务导向性训练/重复经颅磁刺激/手功能/随机对照试验Key words
stroke/intelligent mirror gloves/task-oriented training/repetitive transcranial magnetic stimulation/hand function/randomized controlled trial分类
医药卫生引用本文复制引用
陈晨,孟兆祥,杨康,张敏杰,左亚南,王奎,张熙斌,全逸峰,金星..智能镜像手套任务导向性训练联合低频重复经颅磁刺激对脑卒中患者手功能效果的随机对照试验[J].中国康复理论与实践,2024,30(7):831-838,8.基金项目
扬州市科技计划项目(No.YZ2022099) Yangzhou Science and Technology Plan(No.YZ2022099) （No.YZ2022099）
