中国临床药理学杂志2024，Vol.40Issue(13)：1982-1985,4.DOI:10.13699/j.cnki.1001-6821.2024.13.028
中医药调控有氧糖酵解防治肺癌的研究现状
Research status of regulating aerobic glycolysis by traditional Chinese medicine in prevention and treatment of lung cancer
摘要
Abstract
Aerobic glycolysis(AEG),as the main pathway of energy metabolism of various malignant tumor cells,is involved in the whole process of the occurrence and development of lung cancer,and plays a key role in inducing tumor proliferation,invasion and metastasis.Traditional Chinese medicine monomers and compounds can regulate the expression of related signaling pathways and key proteases and genes by interfering with AEG pathway,promote the apoptosis of lung cancer cells,inhibit the AEG process and the proliferation and growth of lung cancer cells,and thus play an anti-tumor role.Based on this,this paper summarized the biological function of AEG,the mechanism of regulating lung cancer and the intervention mechanism of traditional Chinese medicine,in order to provide new ideas and scientific basis for the development of clinical drugs for lung cancer.关键词
中医药/有氧糖酵解/肺癌/研究进展Key words
traditional Chinese medicine/aerobic glycolysis/lung cancer/research progress分类
医药卫生引用本文复制引用
张茂福,陈玉婵,宋忠阳,陈露露,赵海宏,张志明..中医药调控有氧糖酵解防治肺癌的研究现状[J].中国临床药理学杂志,2024,40(13):1982-1985,4.基金项目
甘肃省科技重大专项基金资助项目(甘科计[2022]1号-25) （甘科计[2022]1号-25）
高端人才承担省级科技计划基金资助项目("长江学者奖励计划")(甘科计[2021]20号-9) （"长江学者奖励计划"）
国家中医药管理局全国名老中医药专家张志明传承工作室建设基金资助项目 （）
甘肃省中西医结合肿瘤临床医学研究中心基金资助项目(18JR2FA001) （18JR2FA001）
甘肃省科技计划基金(重点研发计划)资助项目(22YF7FA) （重点研发计划）
