中国临床药理学杂志2024，Vol.40Issue(13)：1996-2000,5.DOI:10.13699/j.cnki.1001-6821.2024.13.031
辐射对药代动力学的影响
Effects of radiation on pharmacokinetics
摘要
Abstract
Radiation mainly comes from medical radiation,industrial radiation,nuclear waste and atmospheric ultraviolet radiation,etc.,radiation is divided into ionizing radiation and non-ionizing radiation.Studying the effects of ionizing and non-ionizing radiation on drug metabolism,understanding the absorption and distribution of drugs in the body after radiation and the speed of elimination under radiation conditions can provide reasonable guidance for clinical medication.This article reviews the effects of radiation on the pharmacokinetics of different drugs,elaborates the changes of different pharmacokinetics under radiation state,and discusses the reasons for the changes.关键词
药代动力学/辐射/动力学参数/药物代谢酶Key words
pharmacokinetics/radiation/dynamic parameter/drug metabolizing enzyme分类
医药卫生引用本文复制引用
宗杰,张海晖,窦桂芳,孟志云,顾若兰,吴卓娜,朱晓霞,胡瑄,甘慧..辐射对药代动力学的影响[J].中国临床药理学杂志,2024,40(13):1996-2000,5.基金项目
北京市自然科学基金资助项目(7202148) （7202148）
