中国临床药学杂志2024，Vol.33Issue(3)：204-209,6.DOI:10.19577/j.1007-4406.2024.03.007
三叉神经射频消融术预防性使用抗菌药物的有效性、安全性及经济性评价
Efficacy,safety and economic evaluation of prophylactic antibiotics in patients with radiofrequency therapy of trigeminal neuralgia
摘要
Abstract
AIM To evaluate the efficacy,safety and economy of prophylactic use of antibiotics in trigeminal nerve radiofrequency ablation,and to provide reference for clinical rational drug use.METHODS A total of 51 patients who underwent radiofrequency ablation of the trigeminal nerve in the department of pain medicine from January to December 2022 were retrospectively collected.Among them,31 patients were treated with prophylactic antibiotics as the observation group,and 20 patients were treated without prophylactic antibiotics as the control group.The hospitalization time,effective rate,incidence of adverse events and incidence of infection were compared between the 2 groups.The decision tree model was established for economic evaluation.RESULTS There was no significant difference in the length of hospital stay,effective rate and incidence of adverse events between 2 groups(P＞0.05).There was no postoperative infection in 2 groups.According to the cost-effectiveness analysis,the non-prophylactic antibiotic therapy was an economically superior option.CONCLUSION Radiofrequency ablation of trigeminal neuralgia without prophylactic use of antibiotics has shown no significant effect on clinical results and could save medical costs.关键词
三叉神经痛/射频消融/疗效/安全性/经济性Key words
trigeminal neuralgia/radiofrequency ablation/efficacy/safety/economy引用本文复制引用
夏一淼,沈爱宗..三叉神经射频消融术预防性使用抗菌药物的有效性、安全性及经济性评价[J].中国临床药学杂志,2024,33(3):204-209,6.基金项目
皖南医学院教学医院科研专项(编号JXYY202276) （编号JXYY202276）
