中国免疫学杂志2024，Vol.40Issue(7)：1553-1558,6.DOI:10.3969/j.issn.1000-484X.2024.07.035
短链脂肪酸在食物过敏中的免疫调节作用研究进展
Research progress on immunomodulatory effects of short chain fatty acids in food allergy
摘要
Abstract
Food allergy(FA)is a pathological and potentially fatal immune response,whose incidence continues to rise and has become an important public health problem affecting children and adults.Short chain fatty acids(SCFAs),produced by bacteria,through the fermentation of dietary fibre in the gut,played an important role in in pathogenesis of FA.In this review,we will discuss the immunomodulatory effects of SCFAs on the intestinal epithelial cells and various immune cells and their related molecular mecha-nisms in the context of FA,providing new perspectives for the prevention and treatment of FA.关键词
短链脂肪酸/食物过敏/肠上皮细胞/免疫细胞/免疫调节Key words
Short chain fatty acids/Food allergy/Intestinal epithelium cell/Immune cells/Immunomodulatory effects分类
医药卫生引用本文复制引用
于泳璐,谢海,徐灵芝..短链脂肪酸在食物过敏中的免疫调节作用研究进展[J].中国免疫学杂志,2024,40(7):1553-1558,6.基金项目
国家自然科学基金(81701590) （81701590）
山东省自然科学基金(ZR2017BH071) （ZR2017BH071）
大学生创新创业训练计划项目(X2022023). （X2022023）
