食物中唾液酸含量分布研究进展OACSTPCD

[Objective]Sialic acid is widely distributed in various organisms in nature,with more than 50 forms,of which Neu5Ac and Neu5Gc are the two most important forms.Sialic acid has many biological activities such as anti-inflammatory,anti-virus and anti-tumor.It can also be used as a brain nutrient to effectively promote the cognitive development of infants and enhance their learning and memory abili-ties.There is no exact and complete sialic acid concentration data in the Chinese food composition tables.This research aims to summarize and analyze the distribution and concentration of sialic acid in various foods,and speculate possible sialic acid from daily dietary intake.[Method]The relevant research literatures published in China and abroad from the establishment of the database to June 2022 were searched in PubMed,Embase,Web of Science,CNKI database,WanFang database and VIP database.Articles of qualitative and quantitative studies to determine the distribution and content of sialic acid in food were included,including first-hand research data,review,systematic review and other non first-hand research data,and the language was limited to Chinese,English and Italian.Articles that were irrelevant to the topic,repetitive,including incomplete data,and coudn't obtain the full text were excluding.[Result]A total of 11 187 articles were searched,and 35 articles were included as the main evidence of this review,including 15,9,3,2,4 and 4 literatures on milk and milk products,animal foods,vegetables,fruits,cereals and potatoes,and other foods respectively.The research showed that the sialic acid content in edible bird's nest was the highest,which can be as high as 116.2 mg/g,followed by animal food,milk and dairy products.Sialic acid content in animal food was 0-4 574.298 µg/g,and in milk and milk products was 28-1 596 mg/L.Cereals,vegetables and fruits contain trace or no sialic acid,while oils and potatoes do not contain sialic acid.[Conclusion]Animal foods,milk and milk products contain sialic acid.Soybeans,nuts,vegetables,fruits,and cereals contain trace or no sialic acid.