中国输血杂志2024，Vol.37Issue(7)：831-838,8.DOI:10.13303/j.cjbt.issn.1004-549x.2024.07.020
外泌体及其在病毒感染下的双重作用
Exosomes and their dual role under viral infection
韦芊芊 1陈利民 1李玉佳 1李世林1
作者信息
- 1. 中国医学科学院北京协和医学院输血研究所,四川 成都 610052
- 折叠
摘要
Abstract
Exosomes are extracellular vesicles that are released from the cell into the extracellular microenvironment,and are a carrier of biological information transmitted over long distances,which have a dual regulatory effect on the immune system.Studies have shown that viruses can hold the endosomal-exosomal pathway hostage to spread.This review describes the role played by exosomes in viral infections.On the one hand,exosomes can transmit antiviral substances and trigger im-mune responses against viral infections,and on the other hand,exosomes can serve as potential mediators of viral transmis-sion,which have been shown to be closely related to the transmission and immune escape of a variety of viruses.Understand-ing the role of exosomes in viral infections is essential for the detection of viruses in the blood,for improving blood safety,and for the search and development of antiviral drugs.关键词
外泌体/病毒/ESCRT/自噬/免疫Key words
exosomes/virus/ESCRT/autophagy/immunity分类
医药卫生引用本文复制引用
韦芊芊,陈利民,李玉佳,李世林..外泌体及其在病毒感染下的双重作用[J].中国输血杂志,2024,37(7):831-838,8.
