中国现代医学杂志2024，Vol.34Issue(13)：91-96,6.DOI:10.3969/j.issn.1005-8982.2024.13.013
西藏门巴族人群胰岛细胞功能、脂质代谢、炎症反应与中医体质的相关性研究
Study on the correlation between the function of islet cells,lipid metabolism,inflammatory reaction and the constitution of traditional Chinese medicine in Tibetan Menba people
摘要
Abstract
Objective To explore the correlation between islet cell function,lipid metabolism,inflammatory response,and traditional Chinese medicine(TCM)constitution in the Xizang Menba ethnic group.Methods From Januaryto June 2023,a total of 237 people were selected from 6 Menba villages,including Motuo Village,Yadong Village,Langjie Gang Village,Bari Village,Deji Village and Madi Village.The distribution of TCM constitution of the population were analyzed,and the top three people of Chinese medicine constitution were selected to compare the differences in islet cell function,lipid metabolism and inflammatory factor level and so on.Results The main types of TCM constitution arephlegm-dampness,damp-heat and qi-deficiency,accounting for 32.07％,26.16％and 18.57％respectively.There was no significant difference in sex,age and body mass index between the phlegm-dampness,damp-heat and qi-deficiency groups(P＞0.05).The fasting blood glucose and insulin resistance index(HOMA-IR)in the damp-heat group were(4.98±0.83)mmol/L and(1.75±0.32),respectively,which were significantly lower than those in the phlegm-dampnessand qi-deficiency groups(P＜0.05),while HOMA-β was(94.45±9.11),which was higher than those in the phlegm-dampnessand qi-deficiency groups(P＜0.05).The total cholesterol(TC)and triglyceride(TG)in the damp-heatgroup were(3.98±0.99)mmol/L and(1.02±0.29)mmol/L,respectively,which were lower than those in the group of phlegm-dampnessand qi-deficiency(P＜0.05),while high-density lipoprotein cholesterol(HDL-C)was(1.26±0.20)mmol/L,which was higher than that of thephlegm-dampnessand qi-deficiencygroups(P＜0.05).There was no statistically significant difference in serum interleukin-6(IL-6),C-reactive protein(CRP)and tumor necrosis factor-α(TNF-α)among the phlegm-dampness,damp-heat and qi-deficiency groups(P＞0.05).Conclusion The traditional Chinese medicine constitution of Xizang Menba people is dominated by phlegm-dampness,damp-heat and qi-deficiency.Among them,the function of islet cells and lipid metabolism of damp-heat people are better than those of qi-deficiency and yang-deficiency people,and there is no significant difference in inflammatory factors.关键词
胰岛细胞功能/脂质代谢/炎症反应/中医体质/西藏门巴族Key words
islet cell function/lipid metabolism/inflammatory response/traditional Chinese medicine constitution/Xizang Menba nationality分类
医药卫生引用本文复制引用
劳美铃,郭燕,魏爱生,何芬,黄中梁,王文会,邓声敏,杨东山,张珏,阿旺仓决..西藏门巴族人群胰岛细胞功能、脂质代谢、炎症反应与中医体质的相关性研究[J].中国现代医学杂志,2024,34(13):91-96,6.基金项目
广东省医学科学技术研究基金项目(No:B2021340) （No:B2021340）
佛山市自筹经费类科技创新项目(No:2220001004601) （No:2220001004601）
佛山市科技创新项目自筹经费类科技计划项目(No:2020001005589) （No:2020001005589）
