中国现代医学杂志2024，Vol.34Issue(14)：52-58,7.DOI:10.3969/j.issn.1005-8982.2024.14.008
脂联素调节肺部炎症的研究进展
Research progress on the regulatory roles of adiponectin in pulmonary inflammation
摘要
Abstract
Inflammation serves as the common pathophysiological foundation for numerous prevalent lung diseases,including pneumonia,chronic obstructive pulmonary disease(COPD),asthma,and others.Understanding the mechanism underlying the resolution of inflammation may pave the way for novel therapeutic approaches in managing pulmonary inflammatory disorders.Adiponectin,a protein hormone produced and secreted mainly by adipocytes,exerts regulatory effects on inflammation and exhibits protective properties against various inflammatory diseases.Recent studies have shown that adiponectin signaling receptors AdipoRl and AdipoR2 are expressed by lung cells,actively participate in lung physiology,and exert anti-inflammatory activities in COPD,asthma,as well as invasive fungal infections.This review summarizes recent studies exploring the roles of adiponectin in pulmonary inflammatory diseases,aiming to provide clinical insights for the treatment of pulmonary inflammatory diseases.关键词
肺部炎症性疾病/脂联素/炎症消退Key words
pulmonary inflammatory disease/adiponectin/resolution of inflammation分类
医药卫生引用本文复制引用
艾悦,赵雪丹,靳国恩,贾国强..脂联素调节肺部炎症的研究进展[J].中国现代医学杂志,2024,34(14):52-58,7.基金项目
国家重点研发计划(No:2022YFC2403705) （No:2022YFC2403705）
