中国畜牧兽医2024，Vol.51Issue(7)：3041-3055,15.DOI:10.16431/j.cnki.1671-7236.2024.07.029
非洲猪瘟病毒致病机制及防治策略研究进展
Research Progress on the Pathogenic Mechanism and Prevention Strategy of African Swine Fever Virus
摘要
Abstract
African swine fever(ASF)is an acute,hemorrhagic and highly contagious disease,which has a huge negative impact on the world pig industry and food security.There are still no specific drugs and vaccines for the prevention and treatment.African swine fever virus(ASFV)is a large,complex double-stranded DNA virus,but the function of 80％of the encoded proteins is unknown.Therefore,its pathogenic mechanism and drug research status are of great significance for prevention and control.The author summarized the pathogen characteristics,transmission routes and clinical manifestations of ASFV.The latest progress of viral pathogenesis was reviewed from the aspects of virus invasion process,immune cell function changes and related pathway changes.The latest detection technology and vaccine progress of ASFV were introduced.This paper systematically summarized the latest research status of Chinese and Western medicine treatment,the future prospects of traditional Chinese medicine in the prevention and treatment of ASFV were prospected,and the key research directions and related problem solving strategies in the future were put forward,in order to provide reference and practical guidance for the treatment of ASF.关键词
非洲猪瘟病毒(ASFV)/致病机制/预防措施/中药Key words
African swine fever virus(AFSV)/pathogenic mechanism/preventive measures/traditional Chinese medicine分类
农业科技引用本文复制引用
王美乐,于扬帆,徐朋,陈青,安珂兰·安维尔,李姝璇,杨松华,尹素改,冯书营..非洲猪瘟病毒致病机制及防治策略研究进展[J].中国畜牧兽医,2024,51(7):3041-3055,15.基金项目
河南省科技攻关项目(212102110165) （212102110165）
河南省高等学校重点研究计划项目(22B360015) （22B360015）
河南省高校企业横向合作项目(20200011) （20200011）
河南省高等学校重点科研项目计划(23A180014) （23A180014）
