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维生素D辅助治疗危重症疾病的作用机制及研究进展

宋会杰 王玉 吴方方 杜帆帆

中国医学创新2024,Vol.21Issue(19):178-184,7.
中国医学创新2024,Vol.21Issue(19):178-184,7.DOI:10.3969/j.issn.1674-4985.2024.19.041

维生素D辅助治疗危重症疾病的作用机制及研究进展

Mechanism and Research Progress of Vitamin D Adjuvant Therapy for Critical Illness

宋会杰 1王玉 1吴方方 1杜帆帆1

作者信息

  • 1. 河南大学人民医院(河南省人民医院)儿科 河南 郑州 450003
  • 折叠

摘要

Abstract

Critical illness is often accompanied by systemic inflammatory response syndrome.During this period,oxidative products such as reactive oxygen species and nitric oxide increase,while the concentration of protective antioxidants decreases.Imbalanced oxidative stress can lead to cell,tissue and organ damage and increase the mortality of critically ill patients.As an essential nutrient for human metabolism,vitamin D(VD)plays an important role in many physiological processes,and the role of VD in the adjuvant treatment of critically illness cannot be ignored.Recent studies have shown that VD supplementation can effectively improve the prognosis of critically ill patients and is one of the potential means for adjuvant treatment of critically illness.In this paper,the related literature of VD in the treatment of critical illness is summarized,hoping to provide help for further improving the prognosis of critical illness.

关键词

危重症/维生素D/预后

Key words

Critical illness/Vitamin D/Prognosis

引用本文复制引用

宋会杰,王玉,吴方方,杜帆帆..维生素D辅助治疗危重症疾病的作用机制及研究进展[J].中国医学创新,2024,21(19):178-184,7.

基金项目

河南省医学科技攻关计划省部共建项目(SBGJ202102018) (SBGJ202102018)

中国医学创新

1674-4985

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