中国医学创新2024,Vol.21Issue(20):174-178,5.DOI:10.3969/j.issn.1674-4985.2024.20.040
黄连素与心肌纤维化相关性研究进展
Research Progress of Correlation between Berberine and Myocardial Fibrosis
刘志强 1孙经武1
作者信息
- 1. 滨州医学院附属医院心内科 山东 滨州 256603
- 折叠
摘要
Abstract
In recent years,the incidence of cardiovascular disease(CVD)is increasing year by year.Myocardial fibrosis is a pathological change characterized by abnormal proliferation of fibroblasts,excessive deposition and abnormal distribution of collagen.Under pathological conditions(such as hypertension,cardiomyopathy and coronary heart disease),myocardial function is damaged,and a series of changes occur in cardiomyocytes or extracellular matrix and collagen fiber connective tissue.This process is called myocardial remodeling,and myocardial fibrosis is the basic pathological process of myocardial remodeling.Berberine can improve myocardial fibrosis.This article reviews the pathogenesis of myocardial fibrosis and the research progress of berberine and myocardial fibrosis.关键词
黄连素/心肌纤维化/病理性Key words
Berberine/Myocardial fibrosis/Pathological引用本文复制引用
刘志强,孙经武..黄连素与心肌纤维化相关性研究进展[J].中国医学创新,2024,21(20):174-178,5.