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参松养心胶囊联合阿托伐他汀治疗对冠心病患者血脂、动脉粥样硬化的效果OA

Effects of Shensong Yangxin Capsules combined with atorvastatin on blood lipids and atherosclerosis in patients with coronary heart disease

中文摘要英文摘要

目的 探讨参松养心胶囊联合阿托伐他汀治疗对冠心病患者血脂、动脉粥样硬化的效果.方法 选取72例冠心病患者作为研究对象,将其随机分为对照组和研究组,每组36例.对照组行口服阿托伐他汀钙片治疗,研究组在对照组的基础上加用参松养心胶囊治疗,两组均治疗6个月.比较两组治疗前、治疗6个月后的血脂水平、颈动脉内-中膜厚度(IMT)、脉搏波传导速率(PWV),以及治疗期间不良心血管事件的发生情况.结果 治疗6个月后,对照组低密度脂蛋白胆固醇(LDL-C)水平低于治疗前;研究组总胆固醇、甘油三酯、LDL-C水平均低于治疗前,且均低于对照组;研究组颈动脉IMT、PWV均低于对照组(均P<0.05).治疗期间,两组均无不良心血管事件的发生.结论 参松养心胶囊可以改善冠心病患者的血脂代谢,有效调理血脂,并改善患者的动脉粥样硬化,降低急性心血管事件的发生风险.

Objective To investigate the effects of Shensong Yangxin Capsules combined with atorvastatin on blood lipids and atherosclerosis in patients with coronary heart disease.Methods A total of 72 patients with coronary heart disease were selected as research subjects and randomly divided into a control group or a study group,with 36 cases in each group.The control group was treated with oral atorvastatin calcium tablets,on the basis of which the study group was treated with Shensong Yangxin Capsules,and both groups were treated for 6 months.The blood lipids levels,carotid artery intima-media thickness(IMT),and pulse wave velocity(PWV)before treatment and after 6 months of treatment,as well as the occurrence of adverse cardiovascular events during treatment,were compared between the two groups.Results After 6 months of treatment,the low-density lipoprotein cholesterol(LDL-C)level in the control group was lower as compared with that before treatment,the total cholesterol,triglycerides,and LDL-C levels in the study group were also lower as compared with those before treatment and those in the control group;the carotid artery IMT and PWV in the study group were lower than those in the control group(all P<0.05).During the treatment,there was no adverse cardiovascular event in the two groups.Conclusion In the treatment of patients with coronary heart disease,Shensong Yangxin Capsules can improve the blood lipid metabolism,effectively regulate blood lipids,alleviate their atheroscleroses,and reduce the risks of acute cardiovascular events.

宋梦莹;林芃;涂荣会

广西医科大学第一附属医院干部门诊,南宁市 530021

药学

参松养心胶囊冠心病血脂动脉粥样硬化

Shensong Yangxin CapsulesCoronary heart diseaseBlood lipidAtherosclerosis

《内科》 2024 (003)

285-289 / 5

广西中医药管理局自筹经费科研课题(GZZC2020178)

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