中国医学装备2024，Vol.21Issue(7)：17-22,6.DOI:10.3969/j.issn.1672-8270.2024.07.002
基于二维半导体矩阵剂量验证系统实施射波刀治疗患者个体化剂量验证研究
Study on the individualized dose verification of patients with CyberKnife treatment based on dose verification system of SRS MapCHECK matrix
摘要
Abstract
Objective:A dose verification system of two-dimensional semiconductor matrix(SRS MapCHECK)was used to verify the dose of the clinical treatment plan of patients who underwent CyberKnife(CK),which realized rapid verification for individualization of radiotherapy plans of patients through analyzed the γ-passing rates of them.Methods:A total of 253 patients with tumor who received CK clinical treatment in the First Medical Center of Chinese PLA General Hospital from March 2021 to May 2023 were selected.Among of them,121 cases received CK treatment on head,and 30 cases received that on lung,and 102 cases received CK treatment on abdomen and other metastatic tumor.In the MultiPlan treatment plan system,the plan of patient was mapped to the integrated model composed of StereoPHAN model and SRS MapCHECK matrix dose verification system by the means of the plan image center overlap.The dose verification was conducted on the plan of each patient on the basis of ensuring the consistency of the number of beam,direction of beam and the monitor unit.The different γ analysis standards(1%/1 mm,2%/1 mm,3%/1 mm,1%/2 mm,2%/2 mm,3%/2 mm,1%/3 mm,2%/3 mm and 3%/3 mm)were adopted to conduct global analysis of absolute dose for each verification plan,and the threshold(TH)of low dose was set as 10%.Results:The γ passing rates of phantom verification plans of 253 patients were respectively(88.64±5.91)%,(95.43±3.40)%,(97.90±2.06)%,(96.51±2.35)%,(98.15±1.68)%,(99.06±1.12)%,(98.30±1.39)%,(99.09±0.97)%and(99.52±0.63)%under different analysis standards.The γ passing rates of other standards of patients with tumor on different parts were larger than 95%except the analysis result of 1%1 mm standard.The overall analysis result of the deviation of central point dose was(-1.30±2.17)%,among of which the tumor of head,abdominal tumors and other metastatic tumor were about approximately-2%,while that of lung tumors were approximately-3%.The deviation of abdominal and other metastatic tumor was the minimum.The correlation analysis showed that the target volume and the size of the minimum collimator were respectively correlated to the dose deviation of the center.Conclusion:SRS MapCHECK dose verification system can conveniently and quickly realize the individualized verification for the plan of patients who receive CK treatment.关键词
射波刀(CK)/二维半导体矩阵(SRS MapCHECK)/质量保证(QA)/γ通过率Key words
CyberKnife(CK)/Two-dimensional semiconductor matrix(SRS MapCHECK)/Quality assurance(QA)/γ passing rate分类
医药卫生引用本文复制引用
巩汉顺,谷珊珊,吴韶鹃,孙敬林,徐朋飞,刘小亮,白敬民,解传滨..基于二维半导体矩阵剂量验证系统实施射波刀治疗患者个体化剂量验证研究[J].中国医学装备,2024,21(7):17-22,6.基金项目
国家重点研发计划(2022YFC2409502、2022YFC2409503) National Key Research and Development Plan(2022YFC2409502,2022YFC2409503) （2022YFC2409502、2022YFC2409503）
