中国医学装备2024，Vol.21Issue(7)：87-91,5.DOI:10.3969/j.issn.1672-8270.2024.07.015
实时剪切波弹性成像和彩色脉搏波成像技术评估痛风性关节炎患者颈动脉硬度研究
Study on the assessment of real-time SWE and UFPWV techniques in carotid artery stiffness of patients with gouty arthritis
摘要
Abstract
Objective:To explore the application value of real-time shear wave elastography(SWE)and ultrafast pulse wave velocity(UFPWV)techniques in assessing carotid artery stiffness of patients with gouty arthritis(GA).Methods:A total of 80 GA patients admitted to the First People's Hospital of Yibin from August 2022 to July 2023 were selected as GA group.Among of them,24 cases combined with bone erosion who were confirmed by imaging examination,and 56 cases did not combine with bone erosion.In addition,a total of 40 healthy individuals,who underwent physical examinations in our hospital during the same period,were selected as the healthy control group.SWE and UFPWV were used to detect the maximum,minimum and mean values of Young's modulus values of the vessel wall of common carotid artery,and the pulse wave velocity at the beginning of systole(PWVBS)and pulse wave velocity at the end of systole(PWVES)of the vessel wall of common carotid artery of all subjects,and to assess the hardness of circumferential and longitudinal vessel wall of common carotid artery of them.The differences in Young's modulus values,PWVBS and PWVES between two groups were compared.And then,the correlations between bone erosion and Young's modulus values,PWVBS,PWVES of GA patients were further analyzed.Results:The maximum,minimum,mean values,PWVBS and PWVES in the GA group were respectively(78.80±12.38)kPa,(57.83±7.42)kPa,(67.67±8.38)kPa,(7.06±0.59)m/s and(9.50±0.63)m/s,which were significantly higher than those in the healthy control group(t=11.066,8.216,11.751,14.159,19.118,P＜0.05).The maximum,minimum,mean values,PWVBS and PWVES of GA patients with bone erosion were respectively(82.95±6.37)kPa,(59.59±5.29)kPa,(72.18±7.62)kPa,(7.37±0.43)m/s,(10.43±0.47)m/s,which were significantly higher than those[(77.01±5.32)kPa,(57.08±4.73)kPa,(65.73±4.54)kPa,(6.92±0.39)m/s and(9.10±0.41)m/s]of GA patients without bone erosion,the differences were significant(t=4.309,2.099,4.699,4.586,12.720,P＜0.05).Spearman correlation analysis showed that there was significant correlations between maximum,minimum,mean values,PWVBS,PWVES and the combined bone erosion in GA patients(r=0.602,0.421,0.682,0.647,0.732,P＜0.05).Conclusion:SWE and UFPEV techniques can evaluate the hardness of vascular wall of GA patients,and the hardness of circumferential and longitudinal vessel wall of common carotid artery of GA patient is higher than that of healthy person,and the hardness of circumferential and longitudinal vessel wall of common carotid artery of GA patient with bone erosion is higher.关键词
痛风性关节炎(GA)/实时剪切波弹性成像(SWE)/彩色脉搏波成像(UFPWV)/颈动脉硬度Key words
Gouty arthritis(GA)/Real time shear wave elastography(SWE)/Ultra fast pulse wave velocity(UFPWV)/Hardness of carotid artery分类
医药卫生引用本文复制引用
杨小莉,袁红梅,卿建兵,刘纪蓉,鹿文静,刘春洋,韩江涛..实时剪切波弹性成像和彩色脉搏波成像技术评估痛风性关节炎患者颈动脉硬度研究[J].中国医学装备,2024,21(7):87-91,5.基金项目
四川省科学技术基金(2019YJ0710) Science and Technology Fund of Sichuan Province(2019YJ0710) （2019YJ0710）
