中国医药科学2024，Vol.14Issue(12)：4-8,58,6.DOI:10.20116/j.issn2095-0616.2024.12.01
应用CT量化指标CTPI与POLVI评价大叶性肺炎治疗效果的研究
Study on evaluation of efficacy of lobar pneumonia by CT quantitative indicators CTPI and POLVI
摘要
Abstract
Objective To study the quantitative indicators of computed tomography(CT)for the total and volume of lesions in lobar pneumonia and their correlation with inflammatory test indicators,with the aim of evaluating the clinical application value of this group of CT quantitative indicators in evaluating the severity of lobar pneumonia and predicting disease outcomes.Methods A retrospective analysis was conducted based on 167 CT chest examination images of 71 patients with lobar pneumonia diagnosed and treated at the Red Cross Hospital of Yulin City from January 2018 to October 2022.The data were quantified using two CT quantitative indicators,namely CT pneumonia index(CTPI)and the proportion of lung volume involved(POLVI),to obtain the daily change rate of the aggravation group and the improvement group,and compare and statistically analyze the inflammatory test indicators during the same period of examination(within 3 days).Results For CTPI,the median daily change rate of the improvement group was(5.26[3.08,7.96])％/day,while the median daily change rate of the aggravation group was(-5.04[-14.03,-3.49])％/day.For POLVI,the median daily change rate in the POLVI improvement group was(4.34[2.14,7.31])％/day,while the median daily change rate in the aggravation group was(-4.17[-28.33,-2.34])％/day.The quantitative indicators of CT in this group were significantly correlated with the inflammatory test indicators of the same period,such as serum amyloid A and C-reactive protein(P＜0.05).There were no significant differences between the change rate of CT quantitative indicators and the t-test of the change rate of serum amyloid A,C-reactive protein,procalcitonin and erythrocyte sedimentation rate(P＞0.05).Conclusion By further quantifying the basic data of CT examination,CT quantitative indicators such as lesion CTPI and POLVI can be obtained to accurately evaluate the severity and the change rate of lobar pneumonia,which can be promoted and applied in clinical practice.关键词
大叶性肺炎/计算机断层扫描/放射诊断/量化分析/肺炎指数Key words
Lobar pneumonia/CT/Radiodiagnosis/Quantitative analysis/Pneumonia index分类
医药卫生引用本文复制引用
陈强,周颖,赖昌生,岑裕铭,吴碧玉..应用CT量化指标CTPI与POLVI评价大叶性肺炎治疗效果的研究[J].中国医药科学,2024,14(12):4-8,58,6.基金项目
广西壮族自治区卫生健康委员会科研计划课题(Z-K20221822). （Z-K20221822）
