中国医药科学2024,Vol.14Issue(12):188-191,4.DOI:10.20116/j.issn2095-0616.2024.12.45
纳米孔测序检测嗜麦芽窄食单胞菌重症肺炎1例报告
Detection of severe pneumonia caused by Stenotrophomonas maltophilia by nanopore sequencing:a case report
摘要
Abstract
Stenotrophomonas maltophilia pneumonia is a kind of pneumonia caused by Stenotrophomonas maltophilia infection.The conventional pathogen culture method for detection has a low positive rate,high false negative rate and a long cycle,and the pathogenic evidence cannot be accurately obtained in a short term,which affects the prognosis.This paper discussed a relatively faster and more accurate detection method.Being a third-generation sequencing technology,nanopore sequencing(NTS)has advantages over conventional methods in terms of cost and time efficiency,as well as high throughput.In this report,a case of severe hospital-acquired pneumonia caused by pseudomonas maltophilia was detected.The results indicated that the pathogen was caused by Stenotrophomonas maltophilia.This case report provides evidence that NTS can quickly identify pathogens,which is of great significance for clinical diagnosis and treatment.关键词
细菌培养/肺炎/纳米孔测序/嗜麦芽窄食单胞菌Key words
Bacterial culture/Pneumonia/Nanopore sequencing/Stenotrophomonas maltophilia分类
医药卫生引用本文复制引用
黄虎翔,梁超越,吴向春..纳米孔测序检测嗜麦芽窄食单胞菌重症肺炎1例报告[J].中国医药科学,2024,14(12):188-191,4.基金项目
湖北省卫生健康委员会青年医学拔尖人才计划(鄂卫通[2019]48号). (鄂卫通[2019]48号)