中国中西医结合影像学杂志2024，Vol.22Issue(4)：401-405,5.DOI:10.3969/j.issn.1672-0512.2024.04.007
实时剪切波弹性成像及超微血管成像联合D-二聚体在下肢深静脉血栓分期中的应用
Value of shear wave elastography and superb microvasular imaging combined with D-dimer in staging of lower limb deep vein thrombosis
摘要
Abstract
Objective:To explore the value of shear wave elastography(SWE)and superb microvasular imaging(SMI)combined with D-dimer in the staging of lower limb deep vein thrombosis(DVT).Methods:A total of 109 patients with DVT in the lower limbs were enrolled to undergo color Doppler ultrasound(SWE and SMI)for lower limb venous,and all patients were examined for D-dimer level.Results:There were statistical differences in elastic modulus value and SMI score of patients at different stages(all P<0.05).Using the mean elastic modulus value of 16.65 kPa as the cut-off value,SWE had a sensitivity of 55.2%,a specificity of 82.5%and an AUC of 0.72 for the diagnosis of DVT in chronic phase,while using the peak elastic modulus value of 24.85 kPa as the cut-off value,SWE had a sensitivity of 47.8%,a specificity of 90.0%and an AUC of 0.68.Using the SMI score value of 3 points as the cut-off value,SMI had a sensitivity of 75.4%,a specificity of 82.5%and an AUC of 0.81 in the diagnosis of DVT in chronic phase.Binary logistic regression showed that mean elastic modulus value,D-dimer and SMI score(≥3 points)had significant predictive values,and the combination of the three parameters had a sensitivity of 84.1%,a specificity of 87.5%and an AUC of 0.89,and the AUC of the combination was higher than that of the peak and mean elastic modulus in the diagnosis of DVT in chronic phase(P<0.01).Conclusion:The combination of SWE,SMI and D-dimer is valuable for staging diagnosis for DVT.关键词
下肢深静脉血栓/弹性成像技术/超微血管成像/超声检查/D-二聚体Key words
Lower limb deep vein thrombosis/Elastic imaging technology/Superb microvascular imaging/Ultrasonography/D-dimer引用本文复制引用
付遵峰,彭琳,沈雯怡,夏利平,刘燕,张家君..实时剪切波弹性成像及超微血管成像联合D-二聚体在下肢深静脉血栓分期中的应用[J].中国中西医结合影像学杂志,2024,22(4):401-405,5.基金项目
泰安市科技创新发展项目(2020NS185,2021NS433). （2020NS185,2021NS433）
