肿瘤防治研究2024，Vol.51Issue(7)：573-577,5.DOI:10.3971/j.issn.1000-8578.2024.24.0113
个体化经肛提肌外腹会阴联合切除术对女性盆底生物力学影响的有限元分析
Effect of Extralevator Abdominoperineal Excision on Biomechanics of Female Pelvic Floor:A Finite Element Analysis
摘要
Abstract
Objective To explore the effects of four extralevator abdominoperineal excision(ELAPE)procedures on the biomechanics of female pelvic floor through finite element analysis.Methods Six finite element models of the female pelvic floor were established,including a normal model,an ELAPE model,and four individual models.The maximum stress in each model was measured under the same pressure,and the stress distribution was observed.Results The maximum stress of non-levator ani muscle tissues on the partially reserved side and totally removed side of the levator ani muscle were 3.101±0.133 and 4.868±0.123 MPa in individual model 1,respectively,which were lower than the maximum stress in the ELAPE model(5.111±0.081 MPa;both P<0.01).The maximum stress in the non-levator ani muscle tissue were 5.138±0.091 MPa on both sides in individual model 2,which were not significantly different from that in the ELAPE model(P>0.05).The maximum stress of non-levator ani muscle tissues were 4.700±0.105 and 3.653±0.156 MPa in individual models 3 and 4,respectively,which were lower than the maximum stress in the ELAPE model(both P<0.01).Conclusion Three ELAPE procedures,including ELAPE with unilateral levator ani muscle resection plane close to the rectum,and the bilateral pubococcygeal muscle lateral resection of levator ani muscle and levator ani muscle in front of the rectum preserved could decrease stress in the non-levator ani muscle tissue on both sides.The effect is evident on the levator ani muscle partially reserved side of ELAPE with unilateral levator ani muscle resection plane close to the rectum.ELAPE with unilateral levator ani muscle resection plane close to the pelvic wall has no significant reduction effect on the non-levator ani muscle tissue on either side.ELAPE模型(均P<0.01).关键词
直肠肿瘤/ELAPE手术/盆底/生物力学/有限元分析Key words
Rectal neoplasm/ELAPE/Pelvic floor/Biomechanics/Finite element analysis分类
医药卫生引用本文复制引用
王捷夫,路心然,王文鹏..个体化经肛提肌外腹会阴联合切除术对女性盆底生物力学影响的有限元分析[J].肿瘤防治研究,2024,51(7):573-577,5.基金项目
Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-009A) （Specialty）
National Natural Science Foundation of China(No.82373134) （No.82373134）
Science and Technology Development Fund of Tianjin Education Commission for Higher Education(No.2022KJ228) （No.2022KJ228）
Tianjin Medical University Cancer Hospital National Natural Science Foundation Cultivation Program(No.220108) 天津市医学重点学科(专科)建设项目(TJYXZDXK-009A) （No.220108）
国家自然科学基金面上项目(82373134) （82373134）
天津市教委科研计划项目一般项目(2022KJ228) （2022KJ228）
天津医科大学肿瘤医院国家自然基金培育计划(220108) （220108）
