摘要
Abstract
Objective To systematically review the current status and influencing factors of potentially inappropriate medication(PIM)in elderly outpatients in China,and to provide a theoretical basis for reducing the risk of medication in elderly outpatients.Methods PubMed,Web of Science,Cochrane Library,Embase,CNKI,Wanfang and VIP databases were searched by matching subject words and free words for studies on the status and influencing factors of PIM in elderly outpatients in China.The retrieval time was from January 2000 to August 2023.Two to three people completed the literature screening,data extraction and quality evaluation process.Stata 16.0 was used for Meta-analysis.Results A total of 37 literatures were included in this study.The total number of prescriptions was 1 153 750,and the total number of PIM was 219 538.The highest quality score of literature was 9 points,and the lowest was 5 points,and no low-quality literature was found.The results of Meta-analysis showed that the incidence of PIM in elderly outpatients in China was 23.2％.Age(OR=1.21,95％CI:1.16-1.27),insomnia(OR=3.47,95％CI:1.43-8.41),merging coronary heart disease(OR=1.86,95％CI:1.43-2.35),merging disease number(OR=1.37,95％CI:1.24-1.52),number of medications(OR=1.95,95％CI:1.59-2.38),physician's professional title(OR=1.29,95％CI:1.23-1.36)were the influence factors of elderly patients with outpatient PIM happened in China.Conclusion The incidence of PIM in elderly outpatients in China is different.Age,merging coronary heart disease,merging disease number,number of medications and physician's professional title are the promoting factors of PIM.关键词
老年患者/潜在不适当用药/Meta分析Key words
Elderly patients/Potentially inappropriate medication/Meta-analysis分类
医药卫生
