摘要
Abstract
Objective:To explore the effect of percutaneous transhepatic biliary drainage(PTBD)under ultrasound guidance in the interventional treatment of elderly patients with acute cholecystitis(AC).Method:A total of 80 elderly patients with AC admitted to the Third Hospital of Zhangzhou from February 2022 to April 2023 were selected and they were divided into the study group(treated with PTBD intervention)and the control group[treated with laparoscopic cholecystectomy(LC)],40 cases in each group.The perioperative parameters(surgical time,intraoperative bleeding volume,body temperature recovery time,white blood cell recovery time,abdominal drainage time,hospitalization time),stress response[cortisol(Cor),interleukin-6(IL-6),C-reactive protein(CRP)],liver function[total bilirubin(TBIL),alanine aminotransferase(ALT),aspartate aminotransferase(AST),complications between the two groups were compared.Result:The surgical time(32.06±6.11)min,intraoperative bleeding volume(41.31±5.92)mL,body temperature recovery time(1.19±0.25)d,white blood cell recovery time(2.25±0.34)d,abdominal drainage time(2.99±0.42)d and hospitalization time(5.16±0.58)d of the study group were better than those of the control group,the differences were statistically significant(t=11.693,14.291,17.154,16.317,11.182,10.953,P<0.05).The postoperative Cor(249.32±25.86)ng/mL,IL-6(14.03±2.62)ng/L and CRP(15.13±3.15)ng/L of the study group were lower than those of the control group(t=7.022,9.949,5.994,P<0.05).The postoperative TBIL(21.03±2.69)μmol/L,ALT(33.54±3.95)U/L and AST(31.19±4.43)U/L of the study group were lower than those of the control group,the differences were statistically significant(t=9.853,12.682,21.221,P<0.05).The incidence of complications of the study group was 12.50%(5/40),which was lower than 35.00%(14/40)of the control group,the difference was statistically significant(字2=5.591,P<0.05).Conclusion:PTBD intervention therapy for elderly patients with AC has a shorter surgical time,less intraoperative bleeding,faster recovery of body temperature and white blood cells.which can significantly reduce the stress response of the body and improve liver function,with fewer complications.关键词
急性胆囊炎/经皮经肝胆道穿刺引流术/超声/疗效Key words
Acute cholecystitis/Percutaneous transhepatic biliary drainage/Ultrasound/Curative effect
