摘要
Abstract
Objective:To investigate the effect of Ahmed glaucoma valve(AGV)implantation combined with Ranibizumab in the treatment of patients with neovascular glaucoma(NVG).Method:A total of 66 patients with NVG admitted to the Hechi Third People's Hospital from September 2016 to September 2022 were selected as the study objects and divided into two groups according to the computer grouping method,with 33 patients in each group.The control group was treated with AGV implantation,and the observation group was treated with Ranibizumab on the basis of control group.The clinical efficacy,the changes of intraocular pressure and visual acuity,the hemodynamics of ocular artery and the incidence of complications were compared between the two groups.Result:The total effective rate of the observation group was 93.94%,which was higher than 75.76%of the control group,and the difference was statistically significant(P<0.05).After 1 week,1 month and 3 months of treatment,the intraocular pressure level of the observation group was lower than that of the control group,and the best corrected visual acuity(BCVA)of the operative eye was higher than that of the control group,the differences were statistically significant(P<0.05).At 3 months of treatment,end-diastolic flow velocity(EDV)and peak systolic flow velocity(PSV)in observation group were higher than those in control group,and blood flow resistance index(RI)was lower than that in control group,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).Conclusion:AGV implantation combined with Ranibizumab has good clinical efficacy,which can effectively improve the hemodynamic indexes of the eye arteries in patients with NVG,promote the blood circulation of the eye,reduce intraocular pressure,improve visual acuity,and do not increase the incidence of complications.关键词
Ahmed青光眼阀植入术/雷珠单抗/新生血管性青光眼/眼动脉血流动力学Key words
Ahmed glaucoma valve implantation/Ranibizumab/Neovascular glaucoma/Ocular arterial hemodynamics
