中外医学研究2024，Vol.22Issue(18)：160-164,5.DOI:10.14033/j.cnki.cfmr.2024.18.038
生命早期抗生素暴露与过敏性鼻炎相关性的研究进展
Research Progress on Correlation between Early Life Antibiotic Exposure and Allergic Rhinitis
摘要
Abstract
Nowadays,antibiotics are widely used all over the world.Due to factors such as non-standard application and management,related side effects,gradual expansion of application scope and antibiotic residue in the body,researchers have paid more and more attention to the impact of antibiotic exposure on human health,and the correlation with allergic diseases such as allergic rhinitis has become a focus.Infants,in particular,are particularly vulnerable to antibiotics in the early stages of life.The gut microbiome hypothesis has recently emerged as a link between antibiotic exposure and disease development.Probiotics are expected to regulate the immune response of patients with allergic rhinitis,establish a more balanced intestinal flora,so as to reduce patients'allergic symptoms and even prevent allergies,which is one of the popular adjuvant treatment strategies for allergic rhinitis.Therefore,to explore the correlation between antibiotic exposure in early life and allergic rhinitis,optimize antibiotic use and management,and conduct precise intervention in the critical period of the whole life cycle has important practical significance for the primary prevention of allergic rhinitis and improve the quality of life of patients.This article discusses the effect of antibiotic exposure in early life on allergic rhinitis in children and related problems.关键词
生命早期/过敏性鼻炎/抗生素暴露/肠道菌群/益生菌Key words
Early life/Allergic rhinitis/Antibiotic exposure/Intestinal microbiota/Probiotics引用本文复制引用
罗小丫,牛欣冉,徐倩茹,马政,张丽萍,任学宝,侯丽..生命早期抗生素暴露与过敏性鼻炎相关性的研究进展[J].中外医学研究,2024,22(18):160-164,5.基金项目
宁夏自然科学基金项目(2023AAC02065) （2023AAC02065）
宁夏回族自治区重点研发计划项目(2022BEG03105 （）
2021BEG03034) （）
