Bone Research2024，Vol.12Issue(2)：P.438-452,15.DOI:10.1038/s41413-024-00333-9
Matrix stiffening promotes chondrocyte senescence and the osteoarthritis development through downregulating HDAC3
Bowen Fu 1Jianlin Shen 2Xuenong Zou 3Nian Sun 1Ze Zhang 4Zengping Liu 4Canjun Zeng 1Huan Liu 5Wenhua Huang1
作者信息
- 1. Guangdong Medical Innovation Platform for Translation of 3D Printing Application,The Third Affiliated Hospital,Southern Medical University,Guangzhou 510630 Guangdong,China Guangdong Engineering Research Center for Translation of Medical 3D Printing Application,Guangdong Provincial Key Laboratory of Digital Medicine and Biomechanics,National Key Discipline of Human Anatomy,School of Basic Medical Sciences,Southern Medical University,Guangzhou 510145 Guangdong,China Department of Foot and Ankle Surgery,Center for Orthopedic Surgery,The Third Affiliated Hospital,Southern Medical University,Guangzhou 510630 Guangdong,China
- 2. Department of Orthopedics,Affiliated Hospital of Putian University,Putian 351100 Fujian,China Central Laboratory,Affiliated Hospital of Putian University,Putian 351100 Fujian,China
- 3. Guangdong Provincial Key Laboratory of Orthopedics and Traumatology,Department of Spinal Surgery,The First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080 Guangdong,China
- 4. Nanfang Hospital,Southern Medical University,Guangzhou 510515 Guangdong,China Guangzhou Blood Center,Guangzhou 510095 Guangdong,China
- 5. Department of Orthopedics,The Affiliated Traditional Chinese Medicine Hospital,Southwest Medical University,Luzhou 646000 Sichuan,China
- 折叠
摘要
关键词
chondrocyte/osteoarthritis/stiffness分类
医药卫生引用本文复制引用
Bowen Fu,Jianlin Shen,Xuenong Zou,Nian Sun,Ze Zhang,Zengping Liu,Canjun Zeng,Huan Liu,Wenhua Huang..Matrix stiffening promotes chondrocyte senescence and the osteoarthritis development through downregulating HDAC3[J].Bone Research,2024,12(2):P.438-452,15.基金项目
supported by the National Key R&D Program of China(2022YFB4600600) （2022YFB4600600）
National Natural Science Foundation of China(32271181,82301785) （32271181,82301785）
Guangdong Basic and Applied Basic Research Foundation(2020B1515120001) （2020B1515120001）
Sichuan Province Central Guided Local Science and Technology Development Special Program(2023ZYD0072). （2023ZYD0072）
