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首页|期刊导航|Bone Research|Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx

Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx

Ziqian Xiang Pengfei Zhang Chunwang Jia Rongkun Xu Dingren Cao Zhaoning Xu Tingting Lu Jingwei Liu Xiaoxiong Wang Cheng Qiu Wenyang Fu Weiwei Li Lei Cheng Qiang Yang Shiqing Feng Lianlei Wang Yunpeng Zhao Xinyu Liu

Bone Research2024，Vol.12Issue(2)：P.334-348,15.
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Bone Research2024，Vol.12Issue(2)：P.334-348,15.DOI:10.1038/s41413-024-00317-9

Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx

Ziqian Xiang 1Pengfei Zhang 2Chunwang Jia 2Rongkun Xu 2Dingren Cao 3Zhaoning Xu 4Tingting Lu 5Jingwei Liu 6Xiaoxiong Wang 1Cheng Qiu 2Wenyang Fu 2Weiwei Li 7Lei Cheng 2Qiang Yang 8Shiqing Feng 9Lianlei Wang 2Yunpeng Zhao 2Xinyu Liu2

作者信息

  • 1. Department of Orthopaedics,Qilu Hospital of Shandong University,Jinan 250012,China University of Health and Rehabilitation Sciences,Qingdao 226000,China
  • 2. Department of Orthopaedics,Qilu Hospital of Shandong University,Jinan 250012,China
  • 3. Xiangya School of Medicine,Central South University,Changsha 410013,China
  • 4. School of Nursing and Rehabilitation,Shandong University,Jinan 250012,China
  • 5. Department of Pediatrics,Cangzhou Central Hospital,Cangzhou 061011,China
  • 6. Department of Pediatric Surgery,Qilu Hospital of Shandong University,Jinan 250012,China
  • 7. Department of Pathology,Qilu Hospital of Shandong University,Jinan 250012,China
  • 8. Department of Spine Surgery,Tianjin Hospital,Tianjin University,Tianjin 30021,China
  • 9. Department of Orthopaedics,Qilu Hospital of Shandong University,Jinan 250012,China The Second Hospital of Shandong University,Cheeloo College of Medicine,Shandong University,Jinan 250012,China
  • 折叠

摘要

关键词

stress/overload/channel

分类

医药卫生

引用本文复制引用

Ziqian Xiang,Pengfei Zhang,Chunwang Jia,Rongkun Xu,Dingren Cao,Zhaoning Xu,Tingting Lu,Jingwei Liu,Xiaoxiong Wang,Cheng Qiu,Wenyang Fu,Weiwei Li,Lei Cheng,Qiang Yang,Shiqing Feng,Lianlei Wang,Yunpeng Zhao,Xinyu Liu..Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx[J].Bone Research,2024,12(2):P.334-348,15.

基金项目

supported in part by the National Nature Science Foundation(81874022 and 82172483 to Xinyu Liu,82102522 to Lianlei Wang,82072478 to Yunpeng Zhao,82072435 to Qiang Yang,82073437 to Weiwei Li,81930070 to Shiqing Feng,82272548 to Lei Cheng) （81874022 and 82172483 to Xinyu Liu,82102522 to Lianlei Wang,82072478 to Yunpeng Zhao,82072435 to Qiang Yang,82073437 to Weiwei Li,81930070 to Shiqing Feng,82272548 to Lei Cheng）

Key R&D Project of Shandong Province(2022CXGC010503 to Xinyu Liu) （2022CXGC010503 to Xinyu Liu）

Shandong Natural Science Foundation(ZR202102210113 to Lianlei Wang,ZR2020YQ54 to Yunpeng Zhao) （ZR202102210113 to Lianlei Wang,ZR2020YQ54 to Yunpeng Zhao）

Shandong Province Taishan Scholar Project(tsqn202211317 to Lianlei Wang).The authors thank the Translational Medicine Core Facility of Shandong University for the consultation and instrument availability that supported this work. （tsqn202211317 to Lianlei Wang）

Bone Research

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