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RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts

Minhee Kim Jin Hee Park Miyeon Go Nawon Lee Jeongin Seo Hana Lee Doyong Kim Hyunil Ha Taesoo Kim Myeong Seon Jeong Suree Kim Han Sung Kim Dongmin Kang Hyunbo Shim Soo Young Lee

Bone Research2024，Vol.12Issue(2)：P.407-420,14.
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Bone Research2024，Vol.12Issue(2)：P.407-420,14.DOI:10.1038/s41413-024-00326-8

RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts

Minhee Kim 1Jin Hee Park 2Miyeon Go 1Nawon Lee 1Jeongin Seo 1Hana Lee 3Doyong Kim 3Hyunil Ha 4Taesoo Kim 4Myeong Seon Jeong 5Suree Kim 6Han Sung Kim 3Dongmin Kang 7Hyunbo Shim 1Soo Young Lee8

作者信息

  • 1. Department of Life Science,Ewha Womans University,Seoul 03760,South Korea
  • 2. Department of Life Science,Ewha Womans University,Seoul 03760,South Korea The Research Center for Cellular Homeostasis,Ewha Womans University,Seoul 03760,South Korea
  • 3. Department of Biomedical Engineering,Yonsei University,Wonju 26493,South Korea
  • 4. KM Convergence Research Division,Korea Institute of Oriental Medicine,Daejeon 34054,South Korea
  • 5. Chuncheon Center,Korea Basic Science Institute,Chuncheon 24341,South Korea
  • 6. Fluorescence Core Imaging Center and Bioimaging Data Curation Center,Ewha Womans University,Seoul 03760,South Korea
  • 7. Department of Life Science,Ewha Womans University,Seoul 03760,South Korea Fluorescence Core Imaging Center and Bioimaging Data Curation Center,Ewha Womans University,Seoul 03760,South Korea
  • 8. Department of Life Science,Ewha Womans University,Seoul 03760,South Korea The Research Center for Cellular Homeostasis,Ewha Womans University,Seoul 03760,South Korea Multitasking Macrophage Research Center,Ewha Womans University,Seoul 03760,South Korea
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摘要

关键词

osteoclast/inhibited/traffic

分类

医药卫生

引用本文复制引用

Minhee Kim,Jin Hee Park,Miyeon Go,Nawon Lee,Jeongin Seo,Hana Lee,Doyong Kim,Hyunil Ha,Taesoo Kim,Myeong Seon Jeong,Suree Kim,Han Sung Kim,Dongmin Kang,Hyunbo Shim,Soo Young Lee..RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts[J].Bone Research,2024,12(2):P.407-420,14.

基金项目

supported by grants from the National Research Foundation of Korea(RS-2023-00217798 and 2021R1A2C3003675 to S.Y.L.) （RS-2023-00217798 and 2021R1A2C3003675 to S.Y.L.）

by the Korea Basic Science Institute National Research Facilities&Equipment Center grant(2019R1A6C1010020).M.K.was supported in part by scholarship from Ewha Womans University. （2019R1A6C1010020）

Bone Research

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2095-4700

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