Zoological Research2024，Vol.45Issue(4)：P.781-790,10.DOI:10.24272/j.issn.2095-8137.2023.355
Engineered AAV13 variants with enhanced transduction and confined spread
Neng-Song Luo 1Yu-Xiang Cai 1Zeng-Peng Han 2Xiao-Kai Sui 3Wen-Jia Yuan 4Zi-Lian Zhang 5Hao-Dong Guo 6Jie Wang 7Kun-Zhang Lin 5Fu-Qiang Xu8
作者信息
- 1. Wuhan National Laboratory for Optoelectronics,Huazhong University of Science and Technology,Wuhan,Hubei 430074,China
- 2. Shenzhen Key Laboratory of Viral Vectors for Biomedicine,Shenzhen-Hong Kong Institute of Brain Science,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong 518055,China Key Laboratory of Magnetic Resonance in Biological Systems,State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics,National Center for Magnetic Resonance in Wuhan,Innovation Academy for Precision Measurement Science and Technology,Chinese Academy of Sciences,Wuhan,Hubei 430071,China Key Laboratory of Quality Control Technology for Virus-Based Therapeutics,Guangdong Provincial Medical Products Administration,NMPA Key Laboratory for Research and Evaluation of Viral Vector Technology in Cell and Gene Therapy Medicinal Products,Brain Cognition and Brain Disease Institute,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong 518055,China University of Chinese Academy of Sciences,Beijing 100049,China
- 3. Zhongnan Hospital,Wuhan University,Wuhan,Hubei 430072,China
- 4. Brain Case Biotechnology Co.,Ltd.,Shenzhen,Guangdong 518107,China
- 5. Shenzhen Key Laboratory of Viral Vectors for Biomedicine,Shenzhen-Hong Kong Institute of Brain Science,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong 518055,China Key Laboratory of Quality Control Technology for Virus-Based Therapeutics,Guangdong Provincial Medical Products Administration,NMPA Key Laboratory for Research and Evaluation of Viral Vector Technology in Cell and Gene Therapy Medicinal Products,Brain Cognition and Brain Disease Institute,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong 518055,China
- 6. College of Life Sciences,Wuhan University,Wuhan,Hubei 430072,China
- 7. Key Laboratory of Magnetic Resonance in Biological Systems,State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics,National Center for Magnetic Resonance in Wuhan,Innovation Academy for Precision Measurement Science and Technology,Chinese Academy of Sciences,Wuhan,Hubei 430071,China University of Chinese Academy of Sciences,Beijing 100049,China
- 8. Wuhan National Laboratory for Optoelectronics,Huazhong University of Science and Technology,Wuhan,Hubei 430074,China Shenzhen Key Laboratory of Viral Vectors for Biomedicine,Shenzhen-Hong Kong Institute of Brain Science,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong 518055,China Key Laboratory of Magnetic Resonance in Biological Systems,State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics,National Center for Magnetic Resonance in Wuhan,Innovation Academy for Precision Measurement Science and Technology,Chinese Academy of Sciences,Wuhan,Hubei 430071,China Key Laboratory of Quality Control Technology for Virus-Based Therapeutics,Guangdong Provincial Medical Products Administration,NMPA Key Laboratory for Research and Evaluation of Viral Vector Technology in Cell and Gene Therapy Medicinal Products,Brain Cognition and Brain Disease Institute,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong 518055,China University of Chinese Academy of Sciences,Beijing 100049,China Center for Excellence in Brain Science and Intelligence Technology,Chinese Academy of Sciences,Shanghai 200031,China
- 折叠
摘要
关键词
Adeno-associated virus 13/AAV13-YF/AAV13-587-7m8/AAV13-585-7m8/transduction efficiency分类
医药卫生引用本文复制引用
Neng-Song Luo,Yu-Xiang Cai,Zeng-Peng Han,Xiao-Kai Sui,Wen-Jia Yuan,Zi-Lian Zhang,Hao-Dong Guo,Jie Wang,Kun-Zhang Lin,Fu-Qiang Xu..Engineered AAV13 variants with enhanced transduction and confined spread[J].Zoological Research,2024,45(4):P.781-790,10.基金项目
National Science and Technology Innovation 2030 Grant(2021ZD0201003) （2021ZD0201003）
National Natural Science Foundation of China(31830035,31771156,21921004) （31830035,31771156,21921004）
Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32030200) （XDB32030200）
Shenzhen Key Laboratory of Viral Vectors for Biomedicine(ZDSYS20200811142401005) （ZDSYS20200811142401005）
Key Laboratory of Quality Control Technology for Virus-Based Therapeutics,Guangdong Provincial Medical Products Administration(2022ZDZ13)。 （2022ZDZ13）
