广州医药2024，Vol.55Issue(7)：689-704,16.DOI:10.3969/j.issn.1000-8535.2024.07.001
干细胞疗法及神经调控技术在脊髓损伤中的研究进展
Research progress on application of stem cell and neuromodulation technology in spinal cord injury
摘要
Abstract
Spinal cord injury is a highly disabling disease of the central nervous system without effective treatment to date.With the rise of stem cell and tissue engineering,and the breakthrough of neuromodulation technology,it brings new hope to the treatment of spinal cord injury.At present,a number of clinical studies on stem cell-related treatment projects for spinal cord injury have been registered worldwide,which has become a research hotspot.Neuromodulation technology has been playing an important role in the clinical rehabilitation of spinal cord injury.Especially,breakthroughs have been made in the treatment of spinal cord injury by targeted neuromodulation technology in recent years,which is encouraging.Some studies have attempted to combine stem cell therapy and neuromodulation technology to treat spinal cord injuries in an attempt to achieve better effect.This review summarizes the research progress of stem cell therapy and neuromodulation technology in the treatment of spinal cord injury,with the aim of discussing their effect,repair mechanisms,application prospect and various problems to face,and providing further reference for the basic research and clinical transformation of spinal cord injury.关键词
脊髓损伤/干细胞/组织工程/类器官/神经调控技术/再生医学Key words
spinal cord injury/stem cells/tissue engineering/organoids/neuromodulation technology/regenerative medicine引用本文复制引用
张彩玲,兰月,马瑗锾..干细胞疗法及神经调控技术在脊髓损伤中的研究进展[J].广州医药,2024,55(7):689-704,16.基金项目
广东省自然科学基金青年提升项目(2023A1515030254) （2023A1515030254）
广州市科技计划项目(202206010197) （202206010197）
