BDNF和HDL-C与老年帕金森病患者脑白质病变的关系OACSTPCD
Relationship between BDNF and HDL-C and white matter lesions in elderly Parkinson's disease patients
目的 探讨血清脑源性神经营养因子(BDNF)和高密度脂蛋白胆固醇(HDL-C)与老年帕金森病(PD)患者脑白质病变(WML)的关系.方法 筛选116例老年PD患者为研究组,依据Fazckas分级分成PD-WML组和PD组,另选取同期人口学资料匹配的40例健康体检者为对照组.比较不同组别的相关资料,应用多因素Logistic分析PD患者WML的影响因素,受试者工作特征(ROC)曲线分析血清BDNF、HDL-C与PD患者WML的关系.结果 116例P…查看全部>>
Objective To investigate the relationship between serum brain-derived neurotrophic factor(BDNF),high-density lipoprotein cholesterol(HDL-C)and white matter lesions(WML)in elderly Parkinson's disease(PD)patients.Methods Totally 116 elderly patients with PD were strictly selected and recorded as the study group.They were divided into PD-WML group and PD group according to the Fazckas classification.At the same time,40 healthy people matched with demography dat…查看全部>>
华雪;王立娜;马文波
哈尔滨医科大学附属第一医院,黑龙江 哈尔滨 150001哈尔滨医科大学附属第一医院,黑龙江 哈尔滨 150001哈尔滨医科大学附属第一医院,黑龙江 哈尔滨 150001
临床医学
帕金森病脑白质病变脑源性神经营养因子高密度脂蛋白胆固醇相关性
Parkinson's diseaseWhite matter lesions of the brainBrain-derived neurotrophic factorHigh-density lipoprotein cholesterolRelativity
《中国实用神经疾病杂志》 2024 (8)
936-940,5
评论