中国实用神经疾病杂志2024，Vol.27Issue(8)：946-950,5.DOI:10.12083/SYSJ.240044
磁共振扩散加权成像在脑胶质瘤临床评估中的价值
Value of diffusion-weighted imaging in clinical evaluation of brain gliomas
摘要
Abstract
Objective To analyze the value of diffusion-weighted imaging(DWI)in clinical evaluation of brain gliomas.Methods A total of 85 patients with brain gliomas who received examinations January 2020 to August 2023 were selected as the study subjects.All patients were confirmed by postoperative pathology,and examined by GE 1.5T magnetic resonance imaging system.Follow-up was conducted and recurrence status was analyzed.The apparent diffusion coefficient(ADC)values and relative ADC(rADC)values of tumor necrotic and cystic area,tumor peripheral area,tumor parenchyma and contralateral normal white matter were compared.Results The ADC value of contralateral normal white matter((8.32±0.63)×10-4 mm2/s)was significantly lower than those of tumor necrotic and cystic area,tumor peripheral area and tumor parenchyma((25.21±4.27)×10-4 mm2/s,(17.03±3.15)×10-4 mm2/s and(14.33±3.01)×10-4 mm2/s,respectively,P<0.05).The ADC values and rADC values of low-grade gliomas((17.04±2.19)×10-4 mm2/s,1.98±0.22,respectively)were significantly lower than those of high-grade gliomas((12.89±2.55)×10-4 mm2/s,1.57±0.25,respectively,P<0.05).The ADC value of patients with recurrence((13.69±1.90)×10-4 mm2/s)was significantly lower than that of patients without((18.17±2.63)×10-4 mm2/s,P<0.05).The AUC value,sensitivity and specificity of ADC value for diagnosing brain gliomas were 0.967%,91.76%and 100.00%,respectively.The AUC value,sensitivity and specificity of ADC value for diagnosis of different grades of brain gliomas were 0.858,89.19%and 64.58%,respectively.The AUC value,sensitivity and specificity of ADC value for predicting the prognosis of brain gliomas were 0.880,85.29%and 82.35%,respectively.Conclusion DWI is helpful for diagnosis of brain gliomas.In addition,the ADC value can be used to determine the grade of brain gliomas and predict the prognosis.关键词
脑胶质瘤/肿瘤实质/磁共振/磁共振扩散加权成像/表观弥散系数Key words
Brain glioma/Tumor parenchyma/Magnetic resonance imaging/Diffusion-weighted imaging/Apparent diffusion coefficient分类
医药卫生引用本文复制引用
郭庆,陈林..磁共振扩散加权成像在脑胶质瘤临床评估中的价值[J].中国实用神经疾病杂志,2024,27(8):946-950,5.基金项目
四川省中医药管理局科学技术研究专项课题(编号:2022CP5312) （编号:2022CP5312）
