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可降解镁基金属引导骨再生膜的研究现状与展望

陈良伟 韩建民 郭传瑸

华西口腔医学杂志2024,Vol.42Issue(4):415-425,11.
华西口腔医学杂志2024,Vol.42Issue(4):415-425,11.DOI:10.7518/hxkq.2024.2024140

可降解镁基金属引导骨再生膜的研究现状与展望

Research status and prospects of biodegradable magnesium-based metal guided bone regeneration membranes

陈良伟 1韩建民 2郭传瑸1

作者信息

  • 1. 北京大学口腔医学院·口腔医院口腔颌面外科,北京 100081||国家口腔医学中心·国家口腔疾病临床医学研究中心·口腔生物材料和数字诊疗装备国家工程研究中心,北京 100081
  • 2. 国家口腔医学中心·国家口腔疾病临床医学研究中心·口腔生物材料和数字诊疗装备国家工程研究中心,北京 100081||北京大学口腔医学院·中心实验室,北京 100081
  • 折叠

摘要

Abstract

Biodegradable magnesium-based metal guided bone regeneration(GBR)membranes possess excellent me-chanical properties,biodegradability,and osteopromotive capabilities,making them ideal implants for the treatment of maxillofacial bone defects.This review summarizes the current status and future research trends related to magnesium-based GBR membranes.First,the research history and application fields of magnesium-based metals are introduced,and the advantages of the use of magnesium-based materials for GBR membranes,including their mechanical properties,bio-compatibility,osteopromotive performance,and underlying mechanisms are discussed.Finally,this review addresses the current limitations of magnesium-based GBR membranes and their applications and prospects in the field of dentistry.In conclusion,considerable advancements have been in fun-damental and translational research on magnesium-based GBR membranes,which lays a crucial foundation for the treatment of maxillofacial bone defects.

关键词

镁基金属/引导骨再生膜/降解/骨再生/临床转化

Key words

magnesium-based metal/guided bone regeneration membrane/degradation/bone regenera-tion/clinical translation

分类

医药卫生

引用本文复制引用

陈良伟,韩建民,郭传瑸..可降解镁基金属引导骨再生膜的研究现状与展望[J].华西口腔医学杂志,2024,42(4):415-425,11.

基金项目

National Key Research and Development Program of China(2021YFC2400703) (2021YFC2400703)

National Natural Sci-ence Foundation of China(52171234) (52171234)

Beijing Municipal Science and Technology Project(Z211100002921066) (Z211100002921066)

Peking University National Clinical Key Specialty Translation Support Project(PKUSSNKP-T202104) 国家重点研发计划(2021YFC2400703) (PKUSSNKP-T202104)

国家自然科学基金(52171234) (52171234)

北京市科技计划(Z211100002921066) (Z211100002921066)

北京大学口腔医院国家临床重点专科科技成果转化支持项目(PKUSS-NKP-T202104) (PKUSS-NKP-T202104)

华西口腔医学杂志

OA北大核心CSTPCDMEDLINE

1000-1182

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