创伤性脑损伤后创伤后癫痫的危险因素分析OACSTPCD
Analysis of risk factors for posttraumatic epilepsy after traumatic brain injury
目的 探讨创伤性脑损伤(TBI)后创伤后癫痫(PTE)的危险因素.方法 根据是否发生PTE将169 例TBI患者分为PTE组与无PTE组.收集患者的临床资料,并进行比较.采用非参数检验及二元Logistic回归分析PTE的危险因素.结果 与无PTE组比较,PTE组精神症状、GCS评分、影像学检查异常类型、损伤类型、创伤后痫性发作(PTS)比率差异有统计学意义(P<0.05~0.01).二元Logistic回归显示,GCS评分、影像学检查异常类型、精神症状、PTS是PTE的独立危险因素(OR=5.825,95%CI:1.062~31.947,P=0.042;OR=6.942,95%CI:1.542~31.244,P=0.012;OR=31.059,95%CI:9.295~103.786,P<0.001;OR=0.099,95%CI:0.042~0.231,P<0.001).结论 GCS评分、影像学检查异常、精神症状、PTS是TBI后PTE的独立危险因素.
Objective To investigate the risk factors for post-traumatic epilepsy(PTE)after traumatic brain injury(TBI).Methods According to PTE,169 patients with TBI were divided into PTE group and non-PTE group.Clinical data of the patients were collected and compared.Non-parametric test and binary Logistic regression were used to analyze the risk factors of PTE.Results Compared with those in non-PTE group,there were significant differences in psychiatric symptoms,GCS score,abnormal imaging examination type,injury type and post-traumatic seizures(PTS)ratio in the PTE group(P<0.05-0.01).Binary Logistic regression showed that GCS score,abnormal imaging examination type,psychiatric symptoms and PTS were independent risk factors for PTE(OR=5.825,95%CI:1.062-31.947,P=0.042;OR=6.942,95%CI:1.542-31.244,P=0.012;OR=31.059,95%CI:9.295-103.786,P<0.001;OR=0.099,95%CI:0.042-0.231,P<0.001).Conclusion GCS score,abnormal imaging examination type,psychiatric symptoms and PTS are independent risk factors PTE after TBI.
王勇;谢雅彬;张春阳;王雷;李烨;李政堂;佟凌虹;敖铭泽;董艳芳
014010 内蒙古科技大学包头医学院||内蒙古科技大学包头医学院第一附属医院014010 内蒙古科技大学包头医学院内蒙古科技大学包头医学院第一附属医院神经外科
临床医学
创伤性脑损伤创伤后癫痫危险因素
traumatic brain injurypost-traumatic epilepsyrisk factor
《临床神经病学杂志》 2024 (004)
257-260 / 4
国家自然科学基金项目(81960238,82160250)
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