临床神经外科杂志2024，Vol.21Issue(4)：452-455,459,5.DOI:10.3969/j.issn.1672-7770.2024.04.018
烟雾病患者的脑白质损伤及认知功能减退的研究进展
Research progress on white matter damage and cognitive impairment in patients with moyamoya disease
摘要
Abstract
The characteristic of moyamoya disease(MMD)is progressive narrowing or occlusion of the intracranial segment and its proximal branches of the internal carotid artery,leading to ischemic or hemorrhagic stroke with high disability and mortality rates.Many studies show that patients with MMD generally have high signal intensity in the white matter of the brain and varying degrees of white matter damage.At the same time,it has been found that there is a general decline in cognitive function in patients with MMD.After surgical treatment,white matter damage and cognitive function will also be improved to a certain extent,indicating consistency between white matter damage and cognitive function decline in MMD patients.This article reviews the research progress and comprehensive evaluation methods of white matter damage in patients with MMD,and summarizes the improvement of white matter damage and cognitive function in patients with smoke disease after revascularization surgery.关键词
烟雾病/脑白质/认知功能/脑血运重建术Key words
moyamoya disease/brain white matter/cognitive function/cerebral revascularization surgery分类
医药卫生引用本文复制引用
徐永辉,赵金兵,张光绪,仇诚,陈立久,马骏..烟雾病患者的脑白质损伤及认知功能减退的研究进展[J].临床神经外科杂志,2024,21(4):452-455,459,5.基金项目
2022年南京市卫生科技发展专项资金(医学重点科技发展)项目(YKK22136) （医学重点科技发展）
