西罗莫司治疗复杂性脉管异常的研究进展
Advances in research on the treatment of complicated vascular diseases with sirolimus
摘要
Abstract
Vascular anomalies are a group of diseases originating from abnormal blood vessels and/or lymphatic vessels,mostly benign or borderline lesions.There are various treatment methods for vascular anoma-lies,but traditional treatments may be less effective for complicated/refractory vascular anomalies that involve multiple organs or systems,causing severe functional impairment or even life-threatening conditions.Sirolimus,a mammalian target of rapamycin inhibitor,has been found in recent studies to be effective for some complicated vascular anomalies.This article reviews the advances in research on the treatment of complicated vascular anom-alies with sirolimus.关键词
复杂性脉管异常/西罗莫司/雷帕霉素靶蛋白/外科手术/儿童Key words
Complicated Vascular Anomalies/Sirolimus/Mammalian Target of Rapamycin/Surgical Procedures,Operative/Child引用本文复制引用
兰钰茹,周江元,邱桐,吉毅..西罗莫司治疗复杂性脉管异常的研究进展[J].临床小儿外科杂志,2024,23(7):693-696,4.基金项目
国家自然科学基金项目(82273556) （82273556）
四川省科技厅重点研发项目(2022YFS0233、2022YFS0225) （2022YFS0233、2022YFS0225）
四川大学从0到1创新研究项目(2022SCUH0033) （2022SCUH0033）
四川大学医学+信息中心交叉学科建设开放项目(YGJC004) （YGJC004）
四川大学华西医院学科卓越发展1·3·5工程临床研究孵化项目(2019HXFH056、2020HXFH048) （2019HXFH056、2020HXFH048）
四川大学华西医院学科卓越发展1·3·5工程交叉学科创新项目(ZYJC21060) National Natural Science Foundation of China(82273556) （ZYJC21060）
Key Project in the Science &Technology Program of Sichuan Province(2022YFS0233 & 2022YFS0225) （2022YFS0233 & 2022YFS0225）
Project of'0 to 1'of Sichuan U-niversity(2022SCUH0033) （2022SCUH0033）
Med-X Center for Informatics Funding Project(YGJC004) （YGJC004）
1·3·5 Project for Disciplines of Excellence-Clinical Research Incubation Project of West China Hospital of Sichuan University(2019HXFH056 & 2020HXFH048) （2019HXFH056 & 2020HXFH048）
1·3·5 Project for Disciplines of Excellence-Clinical Research Interdis-ciplinary Innovation Project of West China Hospital of Sichuan University(ZYJC21060) （ZYJC21060）
