临床与实验病理学杂志2024，Vol.40Issue(7)：705-709,5.DOI:10.13315/j.cnki.cjcep.2024.07.008
牙源性始基瘤4例临床病理学观察
Clinical and pathological observation of 4 cases of odontogenic primordial tumors
摘要
Abstract
Purpose To investigate the clinicopathological features,diagnosis and differential diagnosis of the primordial odontogenic tumour(POT).Methods Clinical data of 4 cases of jawbone POT were collected.Imaging examination,HE,and immunohistochemical EnVision two-step staining was used to an-alyze their clinical and pathological characteristics,and relevant literatures were reviewed.Results The age arranged from 5 years to 21 years.2 cases were male and 2 case were female.There were 2 cases in maxilla and 2 cases in mandible.The clinical presentation was a slow growing painless mass.Cut sur-face of the tumor was appeared grayish yellow and grayish white,the tumor involved the crown of an unerupted tooth.The tumour consisted of a proliferation of spindled and stellate cells in myx-oid stroma.Surfaced by cuboidal to columnar epithelium forming papillary structures and invaginations.Calcification was observed in 2 cases.Conclusion POT is a rare benign mixed odontogen-ic tumor that is more common in children and adolescents.Mas-tering its characteristic histological morphology can make a cor-rect diagnosis.Local complete resection of the tumor has a good prognosis.关键词
牙源性肿瘤/牙源性始基瘤/病理学特征/免疫表型/预后Key words
odontogenic neoplasm/primordial odontogenic tumour/clinicopathological features/immunohistochemistry/prognosis分类
医药卫生引用本文复制引用
张磊,李慧玲,夏舒,帕克扎提·色依提,陈盛,杨艳,叶传进,泥艳红,黄晓峰..牙源性始基瘤4例临床病理学观察[J].临床与实验病理学杂志,2024,40(7):705-709,5.基金项目
国家自然科学基金(82173159)、南京大学医学院附属口腔医院"3456"骨干人才资助项目(222E309) （82173159）
