妇儿健康导刊2024，Vol.3Issue(15)：22-26,5.
颗粒细胞糖脂代谢对卵母细胞发育影响的研究进展
Research progress on the effects of granulosa cell glucose and lipid metabolism on oocyte development
赵昍朋 1李宝山 1程东凯1
作者信息
- 1. 沈阳菁华医院生殖实验室,辽宁沈阳 110000
- 折叠
摘要
Abstract
Granulosa cells play a key role in establishing and maintaining bidirectional communication between oocytes.Various modes of intercellular material exchange,such as paracrine and gap junction,can facilitate the efficient delivery of granular cell structural components,energy substrates,and signaling molecules to oocytes.The two basic energy metabolic pathways of granulosa cells,namely glucose metabolism and lipid metabolism,are involved in the normal development of oocytes.Pyruvate,as a glycolysis product of granulosa cells,is an important energy substrate for oocyte development.Granulosa cells control the development of oocytes by regulating steroid hormones to regulate the level of hormone in follicles.This article reviews the material exchange between oocytes and granulosa cells,and expounds the roles of glucose metabolism and lipid metabolism in oocyte development.关键词
颗粒细胞/葡萄糖代谢/脂质代谢/卵母细胞Key words
Granulosa cell/Glucose metabolism/Lipid metabolism/Oocyte分类
医药卫生引用本文复制引用
赵昍朋,李宝山,程东凯..颗粒细胞糖脂代谢对卵母细胞发育影响的研究进展[J].妇儿健康导刊,2024,3(15):22-26,5.
