LC-MS/MS测定生活饮用水中27种PFAS化合物OACSTPCD
Determination of 27 PFAS compounds in drinking water by LC-MS/MS
建立了超高效液相色谱-串联质谱(UHPLC-MS/MS)同时测定生活饮用水中 27种PFAS(全氟和多氟烷基物质)的分析方法.水样采用固相萃取富集浓缩的样品前处理过程,离子化模式为:ESI-,多反应监测模式(MRM)进行定性分析;外标法进行定量分析.27 种PFAS化合物在 0.005-0.2mg/L线性浓度范围内具有良好的线性响应,相关系数R2均大于 0.9990.加标回收率为 82.9%-108%,相对标准偏差为 1.6-8.6%,27种PFAS化合物的定量限为 3.0-5.0μg/kg.该方法可用于饮用水中PFAS的检测和分析,具有较高的准确性和可靠性.以期为市场监管部门的监督抽查提供技术支撑.
An ultra-high performance liquid chromatography-tandem mass spectrometry(UHPLC-MS/MS)method was developed for the simultaneous determination of 27 PFAS(perfluorinated and polyfluoroalkyl substances)in drinking water.The water samples were pretreated by solid phase extraction(SPE).The ionization mode was ESI-and the multi-reaction monitoring mode(MRM)was used for qualitative analysis.Quantitative analysis was performed by external standard method.The 27 PFAS compounds showed good linear response in the linear concentration range of 0.005-0.2 mg/L,and the correlation coefficient R2 was greater than 0.9990.The recoveries were 82.9%-108%,the relative standard deviations were 1.6-8.6%,and the limits of quantification for 27 PFAS compounds were 3.0-5.0 μg/kg.The method can be used for the detection and analysis of PFAS in drinking water with high accuracy and reliability.In order to provide technical support for the market supervision department.
王玮;Stephan Altmaier
默克化工技术(上海)有限公司,上海 200120Merck Life Sciences KGaA,Darmstadt,Germany
超高效液相色谱-串联质谱PFAS生活饮用水
Ultra-high performance liquid chromatography-tandem mass spectrometryPFASDrinking water
《现代科学仪器》 2024 (4)
50-56,7
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