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验前概率联合运动平板试验对冠心病的诊断价值及在性别间的差异OACSTPCD

Diagnostic value and gender differences of pre-test probability combined with exercise treadmill test in coronary heart disease

中文摘要英文摘要

目的 探讨验前概率(PTP)联合运动平板试验(ETT)对冠心病(CHD)的诊断价值及在性别间的差异.方法 连续入选 2019 年 6 月至 2023 年 4 月承德市中心医院接收的疑诊CHD患者为研究对象,计算每例入组患者的PTP并进行ETT检查,初步评估罹患CHD概率,并行冠状动脉造影(CAG)检查;以CAG结果为"金标准",探讨PTP联合ETT对CHD诊断价值及在性别间的差异.结果 548 例疑诊CHD患者通过CAG检查,381 例(69.53%)确诊CHD,其中男 221 例(58.01%),女 160 例(41.99%).以CAG检查的结果为"金标准",PTP联合ETT共诊断出 346 例CHD患者,总符合率为 90.81%,其中男 211 例,女 135 例;PTP联合ETT诊断男性患者敏感度为 95.48%、特异度 89.77%、准确度 93.85%、阳性预测值 95.91%、阴性预测值88.76%,与CAG具有极好的一致性(Kappa=0.847).PTP联合ETT诊断女性CHD患者的敏感度84.38%、特异度 79.75%、准确度 82.85%、阳性预测值 89.40%、阴性预测值 71.59%,与CAG具有理想的一致性(Kappa=0.580);PTP联合ETT诊断男性CHD的敏感度、特异度、准确度、阳性预测值、阴性预测值均高于女性患者.结论 PTP联合ETT对CHD具有较高的诊断价值,且对男性CHD患者的诊断效能优于女性患者.

Objective To investigate the diagnostic value and gender differences of pre-test probability(PTP)combined with exercise treadmill test(ETT)in coronary heart disease(CHD).Methods Patients suspected of CHD and admitted to Chengde Central Hospital from June 2019 to April 2023 were consecutively included as research subjects.PTP was calculated for each patient,and ETT was performed.The probability of CHD was preliminary assessed,and coronary angiography(CAG)was performed.Using CAG results as the"gold standard",and the diagnostic value of PTP combined with ETT for CHD and gender differences were explored.Results Among 548 suspected CHD patients who underwent CAG,381 cases(69.53%)were diagnosed with CHD,including 221 males(58.01%)and 160 females(41.99%).Taking CAG results as the"gold standard",346 patients were diagnosed with CHD by PTP combined with ETT,with a total consistent rate of 90.81%,including 211 males and 135 females.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of PTP combined with ETT for diagnosing male CHD patients were 95.48%,89.77%,93.85%,95.91%and 88.76%,respectively,showing excellent consistency with CAG(Kappa=0.847).For female CHD patients,the sensitivity,specificity,accuracy,positive predictive value and negative predictive value of PTP combined with ETT were 84.38%,79.75%,82.85%,89.40%,and 71.59%respectively,demenstrating ideal consistency with CAG(Kappa=0.580).The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of PTP combined with ETT in the diagnosis of male CHD patients were higher than those in female patients.Conclusion PTP combined with ETT has a high diagnostic value for CHD,with better diagnostic efficacy for male CHD patients than for female CHD patients.

姚艳影;杨慧惠;窦杰;高洁;刘蕾;宋智勇;周江;罗东雷

067000 河北省承德市中心医院心血管内科067000 承德,承德医学院050000 石家庄,中国人民解放军联勤保障部队第九八〇医院急诊科

冠心病运动平板试验性别验前概率

Coronary heart diseaseExercise treadmill testGenderPre-test probability

《心脑血管病防治》 2024 (007)

15-17,39 / 4

河北省医学科学研究课题计划(20200236,20200348)

10.3969/j.issn.1009-816x.2024.07.002

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