中国临床药理学杂志2024，Vol.40Issue(15)：2273-2277,5.DOI:10.13699/j.cnki.1001-6821.2024.15.026
中药调控线粒体自噬治疗脑缺血再灌注损伤的研究现状
Research status of traditional Chinese medicine regulation of mitochondrial autophagy in the treatment of cerebral ischemia-reperfusion injury
摘要
Abstract
Mitophagy has a neuroprotective role in cerebral ischemia/reperfusion(I/R)injury,and the regulation of mitophagy may be an important target for the treatment and improvement of prognosis of cerebral ischemia.In recent years,traditional Chinese medicine(TCM)has developed rapidly,and due to its advantages of fewer side effects,significant curative effect,and multiple targets,the regulation of mitophagy by traditional Chinese medicine to improve I/R has become a research hotspot.This article summarizes the important research progress of TCM monomers and TCM compounds in regulating mitophagy in the treatment of I/R injury in recent years,so as to provide research basis and theoretical guidance for the research on the relationship between TCM and mitophagy in I/R injury.关键词
中药/线粒体自噬/脑缺血再灌注损伤/研究现状Key words
Chinese medicine/mitophagy/cerebral ischemia-reperfusion injury/research status分类
医药卫生引用本文复制引用
黎观华,马月辉,周哲屹..中药调控线粒体自噬治疗脑缺血再灌注损伤的研究现状[J].中国临床药理学杂志,2024,40(15):2273-2277,5.基金项目
国家自然科学基金资助项目(82060905) （82060905）
广西自然科学基金资助项目(2023GXNSFAA026431) （2023GXNSFAA026431）
