中国临床药理学杂志2024，Vol.40Issue(15)：2283-2287,5.DOI:10.13699/j.cnki.1001-6821.2024.15.028
中药单体、药对药组及复方治疗子宫内膜异位症的研究现状
Research status of traditional Chinese medicine monomer,drug-to-drug groups and compound formula in the treatment of endometriosis
摘要
Abstract
Interventions for endometriosis(EMs)include surgical excision of lesions and hormonal therapy,which usually have limited efficacy and adverse drug reactions.Traditional Chinese medicine(TCM)has the multi-component and multi-target characteristics,which can help patients achieve good clinical benefits by intervening in different parts of the disease.In this paper,we briefly discuss the modern pharmacology of Sanlang and Curcuma longa,and deeply summarize the possible mechanisms of action of TCM monomer and classical compound extracts and their active ingredients through signal pathways in inflammation,immune system,angiogenesis,hormone regulation,etc.,so as to provide theoretical bases for the clinical use of TCM monomers,drug-to-drug groups and compounds in the treatment of EMs.关键词
中药单体/药对药组/中药复方/子宫内膜异位症/有效成分/信号通路Key words
traditional Chinese medcine monomer/drug-to-drug group/Chinese herbal compound/endometriosis/active ingredient/signaling pathway分类
医药卫生引用本文复制引用
岳斌,陈元欢,武权生,张小花,程渊,梅镐,黄灿灿,张作良,吉秀家..中药单体、药对药组及复方治疗子宫内膜异位症的研究现状[J].中国临床药理学杂志,2024,40(15):2283-2287,5.基金项目
国家自然科学基金资助项目(81760879) （81760879）
国家自然科学基金地区科学基金资助项目(82260949) （82260949）
甘肃中医药大学科创基金资助项目(2019FPZX-2,ZYXT-20-06) （2019FPZX-2,ZYXT-20-06）
