失血性休克复苏液体的演进OACSTPCD
Evolution of resuscitation fluid for hemorrhagic shock——low titer group O whole blood is becoming preferred e-mergent universal bridging resuscitation fluid
血液复苏是严重失血患者的关键急救措施.血液复苏液体的选用,经历了从全血到晶体液/胶体液、晶体液联合红细胞、等比例血液成分的演进过程.近 20 年来,采用低效价抗体O型全血(low titer group O whole blood,LTOWB)作为血液复苏的首选应急通用桥接复苏液,已发展成为大趋势.我们对全血在严重失血患者的应用历史和现状做一介绍,并提出我国采用LTOWB作为首选应急通用血液的进一步论证和验证研究建议.
Timely and effective blood resuscitation is very important for patients with severe blood loss.The resuscitation fluids for hemorrhagic shock have evolved from whole blood to crystalloid/colloid solutions,crystalloid combined with red blood cells,to balanced blood components.In the past 20 years,it is a growing trend that low titer antibody group O whole blood(LTOWB)is used as the preferred universal bridging resuscitation fluid for emergent blood resuscitation.Herein we provide a review of the history and current status of whole blood for patients with severe bleeding and make a suggestion to launch a national implementation research program of LTOWB in China.
王鸿捷;郭永建
北京市红十字血液中心,北京 100083||国家卫生健康标准委员会血液标准专业委员会国家卫生健康标准委员会血液标准专业委员会||福建省血液中心
临床医学
低效价抗体O型全血血液复苏严重失血
low titer group O whole blood(LTOWB)resuscitationhemorrhagic shock
《中国输血杂志》 2024 (008)
953-964 / 12
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