中国实用妇科与产科杂志2024，Vol.40Issue(7)：703-708,6.DOI:10.19538/j.fk2024070109
子宫颈免疫防御机能
The immune defense function of cervix
摘要
Abstract
The cervix is one of the most important tis-sues and organs in the female reproductive system,which can play a role in preventing infection and protecting the female reproductive organs.Cervical immune defense function has its particularity,in-cluding the defense against various bacteria and viruses and other pathogens,and involves sperm,fetal toler-ance.Cervical immune defense function is mainly composed of innate immunity and specific immunity,and is also affected by a variety of factors,especially regulated by sex hormones.Oestrogen and progesterone can directly or indirectly accurately regulate cervical epithelial cells,immune cells and cytokines.During pregnancy,the cervical defense function is facing more unique challenges,because the hormonal changes during this period will make the cervical morphology and cervical immune function appear larger changes.The immune defense function of the cervix may in-fluence each other by the destruction of a pathogen,leading to the imbalance of the entire defense system.Sex hormones also regulate the influence of cervical immune defense,and chemokines may play a role in the repair of cervical immune defense,but further ex-ploration is needed.关键词
子宫颈/免疫防御/影响因素/调节与修复Key words
cervix/immune defense/influencing fac-tors/regulationandrepair分类
临床医学引用本文复制引用
陶陶,曾志,张晓巍,王敏..子宫颈免疫防御机能[J].中国实用妇科与产科杂志,2024,40(7):703-708,6.基金项目
国家重点研发计划(2018YFC1004203) （2018YFC1004203）
