中国实用外科杂志2024，Vol.44Issue(7)：737-740,4.DOI:10.19538/j.cjps.issn1005-2208.2024.07.04
局部进展期中低位直肠癌综合治疗焦点问题
Key issues in comprehensive therapy of locally advanced mid-low rectal cancer
摘要
Abstract
The combination of neoadjuvant chemotherapy and total mesorectal excision(TME)has become the standard treatment for locally advanced mid-low rectal cancer.Along with the progress in the concept of multimodality therapy,the improvement in surgical techniques,and especially the upgradation in patients'requirement for survival quality,transanal total mesorectal excision(taTME),optimization of neoadjuvant immunotherapy,and watch and wait strategy have gradually become the key issues in synthetic therapy for locally advanced mid-low rectal cancer.Based on these new concepts,methods,and technologies in clinical research and practice,an increasing number of locally advanced mid-low rectal cancer patients achieve oncological regression or even complete tumor remission through preoperative treatment and obtain the opportunity to preserve the rectum without surgery or receive curative anal preservation surgery,further promoting the development of individualized and precise diagnosis and treatment models for locally advanced mid-low rectal cancer.关键词
局部进展期直肠癌/新辅助免疫治疗/等待观察/经肛全直肠系膜切除Key words
locally advanced rectal cancer/neoadjuvant immunotherapy/watch and wait/transanal total mesorectal excision分类
医药卫生引用本文复制引用
姚宏伟,杨正阳,张忠涛..局部进展期中低位直肠癌综合治疗焦点问题[J].中国实用外科杂志,2024,44(7):737-740,4.基金项目
国家重点研发计划资助项目(No.2017YFC0110904) （No.2017YFC0110904）
首都医科大学结直肠肿瘤临床诊疗与研究中心基金项目(No.1192070313) （No.1192070313）
北京市医院管理中心扬帆计划临床技术创新项目基金项目(No.ZLRK202302) （No.ZLRK202302）
