中国实用外科杂志2024，Vol.44Issue(7)：761-767,7.DOI:10.19538/j.cjps.issn1005-2208.2024.07.09
结直肠癌肝脏寡转移治疗策略
Treatment strategies for colorectal liver oligometastases
摘要
Abstract
Colorectal liver oligometastasis(CRLOM)refers to the controlled(already resected or resectable)primary colorectal cancer with a limited number of liver metastases that can be safely and effectively treated locally.The incidence rate of CRLOM is high but its prognosis is poor.At present,comprehensive treatment strategies based on surgery are mainly used,including conversion therapy,neoadjuvant therapy,resection of liver metastases,postoperative adjuvant therapy,etc.Among them,conversion therapy is divided into residual liver volume(FLR)conversion and oncological conversion,and FLR conversion includes portal vein embolization(PVE),portal vein ligation(PVL),associated liver partition and portal vein ligation for staged hepatectomy(ALPPS)and liver vein deprivation(LVD).Local treatment measures such as ablation,transcatheter intra-arterial therapy,and radiation therapy can be applied to improve the surgical efficacy of CRLOM or unresectable CRLOM.Liver transplantation has a good therapeutic effect on patients with unresectable CRLOM who have undergone strict screening.To develop personalized treatment strategies,the actual situation of CRLOM patients should be taken into consideration.关键词
结直肠癌肝转移/手术/综合治疗Key words
colorectal liver metastases/surgery/comprehensive treatment分类
医药卫生引用本文复制引用
黄罡,余建,周伟平..结直肠癌肝脏寡转移治疗策略[J].中国实用外科杂志,2024,44(7):761-767,7.基金项目
国家自然科学基金青年科学基金项目(No.82002458) （No.82002458）
