长脉宽1064nm Nd:YAG激光与2940nm Er:YAG激光联合胶原蛋白水光注射在面部年轻化中的临床应用OA

Objective Evaluate the effectiveness of Fotona 4D Pro combined with collagen intradermal injection in facial rejuvenation using split face mode.Methods This study included 35 subjects with a need for facial rejuvenation treatment,and their faces were randomly divided into control side and treatment side.The control side was treated with Fotona 4D Pro,while the treatment side was treated with Fotona 4D Pro combined with Fillderm collagen intradermal injection.The differences in the degree of facial rejuvenation on both sides were compared before treatment and at 2,4,8,and 12 weeks after treatment.Results The skin retraction time,skin elasticity index,dermal thickness,skin brightness,skin moisture content and transepidermal water loss on the treatment side were significantly different from those before treatment(P<0.05);The skin retraction time,dermal thickness,skin brightness,skin moisture content and transepidermal water loss of the control side were significantly different from those before treatment(P<0.05);There was no significant difference between the two sides of the face in basline,but there was a significant difference in the skin thickness between the two sides of the face from 2 weeks after treatment(P<0.01);After 8 weeks of treatment,there were statistically significant differences in skin rebound time and skin elasticity index on both sides of the face(P<0.05);There was no statistically significant difference in skin brightness,skin moisture content,and transepidermal water loss between the two sides of the face at different time points(P>0.05).Conclusions After treatment with Fotona 4D Pro,collagen intradermal injection can be used immediately to achieve synergistic effects,immediate supplementation,and sustained promotion of collagen regeneration