疏肝解郁与散结消癥汤联合经脐单孔腹腔镜手术治疗卵巢囊肿的效果OA
Effect of Shugan Jieyu and Sanjie Xiaozheng Decoction Combined with Transumbilical Single-port Laparoscopic Surgery on Ovarian Cysts
目的 探讨疏肝解郁、散结消癥汤联合经脐单孔腹腔镜手术治疗卵巢囊肿的临床效果.方法 选取2021年6月至2022年6月于启东市妇幼保健院就诊的卵巢囊肿患者80例作为研究对象,按随机数字表法分为观察组(n=40)和对照组(n=40).观察组给予经脐单孔腹腔镜手术联合疏肝解郁、散结消癥汤加减治疗,对照组给予经脐单孔腹腔镜手术治疗.比较两组临床疗效和术后相关指标[视觉模拟评分法(VAS)评分、肛门排气时间、切口愈合时间、住院时间],记录两组治疗前后中医证候积分(主症积分、次症积分),观察术后当天和术后3 d炎症因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、C-反应蛋白(CRP)]水平以及治疗前后卵巢功能[促卵泡激素(FSH)、黄体生成素(LH)和雌二醇(E2)],并记录两组术后并发症发生率.结果 观察组治疗有效率高于对照组(P＜0.05);两组肛门排气时间、切口愈合时间比较差异无统计学意义(P＞0.05);但观察组术后3 d的VAS评分低于对照组,住院时间短于对照组,差异有统计学意义(P＜0.05);治疗后两组各项中医主症、次症积分降低,且观察组低于对照组,差异有统计学意义(P＜0.05);治疗后两组TNF-α、IL-6、CRP水平降低,且观察组低于对照组,差异有统计学意义(P＜0.05);治疗后两组FSH、LH、E2 水平降低,且观察组低于对照组,差异有统计学意义(P＜0.05);观察组术后并发症发生率与对照组比较,差异无统计学意义(P＞0.05).结论 疏肝解郁、散结消癥汤联合经脐单孔腹腔镜手术治疗卵巢囊肿的临床疗效更佳,能有效改善患者症状和卵巢功能,减轻炎症反应,且并发症较少.
Objective To explore the clinical effect of Shugan Jieyu and Sanjie Xiaozheng decoction combined with transumbilical single-port laparoscopic surgery in the treatment of ovarian cysts.Methods A total of 80 patients with ovarian cysts who were treated in Qidong Maternal and Child Health Hospital from June 2021 to June 2022 were selected as the study objects and divided into observation group(n=40)and control group(n=40)according to random number table method.The observation group was given transumbilical single-port laparoscopic surgery combined with Shugan Jieyu and Sanjie Xiaozheng decoction while the control group was given transumbilical single-port laparoscopic surgery.The clinical efficacy and postoperative related indicators[Visual Analogue Scale(VAS),anal exhaust time,incision healing time,hospital stay]were compared between the two groups,and The TCM syndromes scores(primary syndromes scores,secondary syndromes scores)were recorded in both groups before and after treatment.The differences in inflammatory factors[tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),C-reactive protein(CRP)]before surgery and at 3 days after surgery and ovarian function[follicle-stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2)]before and after treatment were observed,and the incidence rates of postoperative complications in the two groups were recorded.Results The effective rate of the observation group was higher than that of the control group(P＜0.05).There was no significant difference in anal exhaust time and incision healing time between the two groups(P＞0.05).However,the VAS score of the observation group at 3 days after surgery was lower than that of the control group,and the length of hospitalization was shorter,with statistical significance(P＜0.05).After treatment,the scores of TCM main and secondary diseases in the two groups were decreased,and the observation group was lower than the control group,the difference was statistically significant(P＜0.05).After treatment,the levels of TNF-α,IL-6 and CRP in two groups were decreased,and the observation group was lower than the control group,the difference was statistically significant(P＜0.05).After treatment,the levels of FSH,LH and E2 of the two groups were decreased,and the observation group was lower than the control group,the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of postoperative complications between the observation group and the control group(P＞0.05).Conclusion Shugan Jieyu,Sanjie Xiaoshi Decoction combined with transumbilical single-hole laparoscopic surgery has better clinical efficacy in the treatment of ovarian cysts,which can effectively improve symptoms and ovarian function,reduce inflammation,and have fewer complications.
彭洁琼
启东市妇幼保健院妇产科,江苏南通 226200
临床医学
卵巢囊肿经脐单孔腹腔镜手术疏肝解郁、散结消癥汤临床疗效
Ovarian cystsTransumbilical single-port laparoscopic surgeryShugan Jieyu and Sanjie Xiaozheng decoctionClinical efficacy
《中国药物经济学》 2024 (007)
39-43 / 5
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